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MetabolomicsDeficient Endoplasmic Reticulum-Mitochondrial Phosphatidylserine Transfer Causes Liver Disease
Non-alcoholic fatty liver is the most common liver disease worldwide. Here, we show that the mitochondrial protein mitofusin 2 (Mfn2) protects against liver disease. Reduced Mfn2 expression was detected in liver biopsies from patients with non-alcoholic steatohepatitis (NASH). Moreover, reduced Mfn2...
2018-01-25 | MTBLS600 | MetaboLights
ProteomicsAn integrated global analysis of compartmentalized HRAS signaling - Ras IP
Modern omics technologies allow us obtaining global information on different types of biological networks. However, integrating these different types of analyzes into a coherent framework for a comprehensive biological interpretation remains challenging. Here, we present a conceptual framework that ...
ORGANISM(S): Homo sapiens (Human) 
2019-03-08 | PXD012505 | Pride
Hras hrasv12 hela 
ProteomicsAn integrated global analysis of compartmentalized HRAS signaling - Phosphoproteomics
Modern omics technologies allow us obtaining global information on different types of biological networks. However, integrating these different types of analyzes into a coherent framework for a comprehensive biological interpretation remains challenging. Here, we present a conceptual framework that ...
ORGANISM(S): Homo sapiens (Human) 
2019-03-08 | PXD012506 | Pride
Ras phosphoproteomics minetei localisation 
UnknownDevelopment and validation of a risk score for chronic kidney disease in HIV infection using prospective cohort data from the D:A:D study.
Not available
S-EPMC4380415 | biostudies-literature
UnknownNot only Alagille syndrome. Syndromic paucity of interlobular bile ducts secondary to HNF1β deficiency: a case report and literature review.
Not available
S-EPMC6385394 | biostudies-literature
ProteomicsONGOING CHROMOSOMAL INSTABILITY ACROSS ANEUPLOID SUBTYPES OF CHILDHOOD B-CELL ACUTE LYMPHOBLASTIC LEUKEMIA ASSOCIATES WITH DISEASE PROGRESSION
Chromosomal instability (CIN), defined as an increased occurrence of chromosome segregation errors during cell division, is a prominent form of genomic instability (Bakhoum and Avi Landau, 2017). It is the major cause of aneuploidy, an imbalanced complement of whole chromosomes or chromosome arms, w...
ORGANISM(S): Homo sapiens (Human) 
2023-09-15 | PXD042785 | Pride
Aneuploidy B-cell acute lymphoblastic leukemia Childhood b-all Chromosomal instability 
ProteomicsEMRE is an Essential Component of the Mitochondrial Calcium Uniporter Complex
Not available
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2015-04-03 | MSV000079095 | MassIVE
UnknownBody mass index as a predictive factor for efficacy of adjuvant taxane-based chemotherapy in early-stage breast cancer patients: A pooled analysis from adjuvant GEICAM Spanish Breast Cancer Group and TRIO Translational Research in Oncology Group studies.
Not available
S-EPMC12178099 | biostudies-literature
UnknownIntermediate endpoints as surrogates for long-term outcomes in breast cancer adjuvant chemotherapy trials.
Not available
S-EPMC12450318 | biostudies-literature
UnknownStructural brain abnormalities in the common epilepsies assessed in a worldwide ENIGMA study.
Not available
S-EPMC5837616 | biostudies-literature
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