Sort   by:  
 Page size 
ProteomicsSequence analysis of Giardia virus proteins by LC-MS/MS
Giardiasis, caused by the protozoan parasite Giardia duodenalis, is an intestinal diarrheal disease affecting almost one billion people worldwide. A small endosymbiotic dsRNA viruses, G. lamblia virus (GLV), genus Giardiavirus, family Totiviridae, might inhabit human and animal isolates of G. duoden...
ORGANISM(S): Giardia intestinalis (Giardia lamblia) 
2021-07-05 | PXD025785 | Pride
Proteomics Giardia duodenalis Giardiavirus 
ProteomicsProteomic analysis of NK cell-derived extracellular vesicles.
Natural killer (NK) cells contribute to immunosurveillance and first-line defense in the control of tumor growth and metastasis diffusion. NKEVs are constitutively secreted, are biologically active, reflect the protein and genetic repertoire of their originating cells and exert anti-tumor activity i...
ORGANISM(S): Homo sapiens (Human) 
2020-04-03 | PXD014894 | Pride
Proteomics natural killer cells exosomes microvesicles 
ProteomicsStructural basis of ubiquitination mediated by protein splicing in early Eukarya
This study is part of a project focused on the study of the ability of inteins to perform protein splicing. Our aim, in particular, is to characterize by mass spectrometry the splicing products of the ubl4- BIL2-ubl5 and of Ras, which strongly interacts with ubl4- BIL2-ubl5 precursor.
ORGANISM(S): Escherichia coli 
2021-01-18 | PXD020525 | Pride
Ubiquitin protein splicing 
ProteomicsProteomics of Clostridium butyricum strains in aerobic and anaerobic conditions
Analysis of proteins from botulinum neurotoxin-producing Clostridium butyricum strains grown upon exposure to air. This strain usually lives in anaerobic environments, but we found that it is able to keep growing and producing toxin in vitro upon exposure to air. This project analyzes the proteins d...
ORGANISM(S): Clostridium butyricum E4 str. BoNT E BL5262 
2019-04-18 | PXD013383 | Pride
Clostridium butyricum proteomics 
ProteomicsThe role of actin II in the mosquito stages of Plasmodium berghei
The aim of this work is to characterize the Plasmodium berghei actin II during mosquito stages with special focus on post-translational modification of histidine.
ORGANISM(S): Plasmodium berghei 
2023-02-16 | PXD033378 | Pride
Actin plasmodium methylation 
ProteomicsLC-MS/MS analysis of NGF proteins purified from cerebrospinal fluid
The aim of the project is to develop and validate a new method to measure proNGF in the cerebrospinal fluid of living patients, and to use it as a biomarker of Alzheimer’s disease (AD). This method, a novel proNGF immunoassay, is based on molecular size separation by capillary electrophoresis and is...
ORGANISM(S): Homo sapiens (Human) Rattus norvegicus (Rat) 
2022-02-17 | PXD025883 | Pride
Cerebrospinal fluid Alzheimer Mass spectrometry Ngf 
ProteomicsMLC phosphorylation by the kinase CaMKII
MLC1 is membrane protein highly expressed by brain perivascular astrocytes. Mutations in MLC1 account for megalencephalic leukoencephalopathy with subcortical cysts (MLC), an incurable leu-kodystrophy characterized by macrocephaly, brain edema and cysts, myelin vacuolation and as-trocyte swelling, t...
ORGANISM(S): Homo sapiens (Human) 
2022-10-13 | PXD030549 | Pride
Mlc megalencephalic leukoencephalopathy phosphorylation mass spectrometry 
ProteomicsStructural obstruction to full DNA replication in the chromatin of terminally differentiated skeletal muscle cells
Terminal cell differentiation is often associated with permanent withdrawal from proliferation, termed the postmitotic state. Though widespread among vertebrates and determinant for their biology, the molecular underpinnings of this state are poorly understood. Postmitotic skeletal muscle myotubes c...
ORGANISM(S): Mus Musculus (ncbitaxon:10090) 
2025-01-13 | MSV000096839 | MassIVE
ProteomicsProteomic signature of plasma-derived exosomes in different stages of melanoma patients.
Exosomes, extracellular vesicles of 30-150 nm, are released by normal and tumor cells. These nanovesicles play a major role in cell communication and can be found in biological fluids as carriers of biomarkers. Tumor exosomes can inhibit immune responses, mediate drug resistance and transform mesenc...
ORGANISM(S): Homo sapiens (Human) 
2023-05-09 | PXD024434 | Pride
Exosomes Proteomics Melanoma 
Sort   by:  
 Page size