Sort   by:  
 Page size 
GenomicsIdentification of CaMKII-dependent H3S28p target genes
To identify direct CaMKII-dependent downstream genes of H3S28p we used chromatin-immunoprecipitation followed by massive parallel DNA sequencing (ChIPseq) analysis of isolated adult murine cardiomyocytes from CamKII WT as well as from CaMKIIγ/CaMKIIδ double knockout (DKO) . DKO and WT cells were sub...
ORGANISM(S): Mus musculus 
2019-06-13 | E-MTAB-8011 | biostudies-arrayexpress
TranscriptomicsCaMKII inhibition in smooth muscle cells controls Ang-II-induced gene transcription in the aorta
The Ca2+/calmodulin-dependent kinase II is expressed in smooth muscle and believed to mediate intracellular calcium handling and calcium-dependent gene transcription. CaMKII is activated by Angiotensin-II. The multifunctional calcium/calmodulin-dependent kinase II (CaMKII) is activated by Angiotensi...
ORGANISM(S): Mus musculus 
2015-07-01 | E-GEOD-64613 | biostudies-arrayexpress
TranscriptomicsCaM Kinase II mediates maladaptive post-infarct remodeling but not acute myocardial ischemia/reperfusion injury
Calcium/calmodulin-dependent protein kinase II (CaMKII) was suggested to mediate ischemic myocardial injury and adverse cardiac remodeling. However, the specific functions of the CaMKII isoforms and splice variants in ischemia/reperfusion (I/R) injury have not been investigated yet. Thus, we studied...
ORGANISM(S): Mus musculus 
2014-09-08 | E-GEOD-58486 | biostudies-arrayexpress
TranscriptomicsTranscription profiling by array of hippocampi from wild type and alpha-CaMKII+/- mice
Comparison of the hippocampus of alpha-CaMKII+/- mice with control
ORGANISM(S): Mus musculus 
2008-10-04 | E-MEXP-962 | biostudies-arrayexpress
GenomicsIdentification of CaMKII-dependent H3S28p target genes
Identification of CaMKII-dependent H3S28p target genes
PRJEB32860 | ENA
TranscriptomicsGene expression microarray analysis on the dentate gyrus of alpha-CaMKII HKO mice
We previously found that mice with heterozygous knockout of the alpha-isoform of calcium/calmodulin-dependent protein kinase II (alpha-CaMKII HKO mice) show various dysregulated behaviors, including cyclic variations in locomotor activity (LA), suggesting that alpha-CaMKII HKO mice may serve as an a...
ORGANISM(S): Mus musculus 
2016-03-29 | E-GEOD-68293 | biostudies-arrayexpress
Proteomicsβ-OHB Reduces Reinstatement of Cocaine Conditioned Place Preference Through Hippocampal CaMKII-α β-Hydroxybutyrylation
Studies have shown the therapeutic effects of a ketogenic diet (KD) on epilepsy, but the effect of KD on drug reinstatement is largely unclear. This study aims to investigate whether KD consumption possesses therapeutic potential for cocaine reinstatement and the molecular mechanism. We find that KD...
ORGANISM(S): Mus musculus (Mouse) 
2022-11-30 | PXD037321 | Pride
Β-ohb  cocaine reinstatement  camkii-α β-hydroxybutyrylation 
GenomicsSkeletal muscle from CaMKII knockout mice subjected to endurance training
Skeletal muscle from CaMKII knockout mice subjected to endurance training
PRJNA1238766 | ENA
GenomicsIdentification of CaMKII splice variants expressed in the human hippocampus
Identification of CaMKII splice variants expressed in the human hippocampus
PRJNA644901 | ENA
ProteomicsMitochondrial CaMKII phosphoproteome.
Mice overexpressing CaMKII in myocardial mitochondria have dilated cardiomyopathy that appears to be exclusively driven by metabolic defects that lead to reduced ATP production. Phosphoproteomics study of mitochondrial proteins supports the metabolomics data.
ORGANISM(S): Mus musculus (Mouse) 
2020-07-31 | PXD004631 | Pride
Heart Tiimac Phosphoproteome Mitochondria Lc-ms/ms 
Sort   by:  
 Page size