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Transcriptomicssingle cell RNAseq of memory B cells in the context of rituximab-treated ITP patients
Rituximab (RTX) is widely used as a first-line therapeutic strategy in B cell-mediated autoimmune diseases. However, a large proportion of patients either do not respond to the treatment or relapse during B cell reconstitution. Primary immune thrombocytopenia (ITP) is a prototypic B cell mediated au...
ORGANISM(S): Homo sapiens 
2021-01-31 | E-MTAB-9955 | biostudies-arrayexpress
TranscriptomicsSingle cell RNAseq analysis of anti-Vaccinia long-lived memory B cells (CEL-seq2)
Memory B cells represent one of the pillar of humoral protection and are found in the circulation and secondary lymphoid organs several decades after initial pathogen or vaccine encounter. The exact cellular and biological mechanisms allowing long-term survival of quiescent cells in such a fluctuati...
ORGANISM(S): Homo sapiens 
2022-09-19 | E-MTAB-11626 | biostudies-arrayexpress
TranscriptomicsGenome Wide Analysis of Immune Activation in Human T and B Cells Reveals Distinct Classes of Alternatively Spliced Genes
Alternative splicing of pre-mRNA is a mechanism that increases the protein diversity of a single gene by differential exon inclusion during post-transcriptional processing. While alternative splicing is established to occur during lymphocyte activation, little is known about the role it plays during...
ORGANISM(S): Homo sapiens 
2010-04-08 | E-GEOD-14352 | biostudies-arrayexpress
UnknownPROTOCOL: Searching and reporting in Campbell Collaboration systematic reviews: An assessment of current methods
Not available
S-EPMC8988751 | biostudies-literature
UnknownInferring a role for methylation of intergenic DNA in the regulation of genes aberrantly expressed in precursor B-cell acute lymphoblastic leukemia.
Not available
S-EPMC5478429 | biostudies-literature
UnknownA pilot, parallel-group, blinded, placebo-controlled, randomise<b>D</b>, p<b>R</b>agmatic clinical trial investigating the <b>E</b>ffect of temazep<b>AM</b> on objective and subjective measures of sleep in critically ill patients (the DREAM trial).
Not available
S-EPMC12933563 | biostudies-literature
TranscriptomicsTranscription profiling by array of Burkholderia cenocepacia J2315 grown at 20C or 37C
B. cenocepacia J2315 was grown on LB medium to mid-stationary phase at O.D. 0.5 at 150 rpm in a shaking incubator at two different temperatures: 37 degrees and 20 degrees centigrade.
ORGANISM(S): Burkholderia cenocepacia 
2012-01-01 | E-MEXP-2789 | biostudies-arrayexpress
UnknownB cell adaptor for PI3-kinase (BCAP) modulates CD8+ effector and memory T cell differentiation.
Not available
S-EPMC6122975 | biostudies-literature
UnknownEnvironmental Pollutant Ozone Causes Damage to Lung Surfactant Protein B (SP-B).
Not available
S-EPMC4571829 | biostudies-literature
UnknownB-cell intrinsic and extrinsic signals that regulate central tolerance of mouse and human B cells.
Not available
S-EPMC8986553 | biostudies-literature
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