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MetabolomicsProteome allocations change linearly with the specific growth rate of Saccharomyces cerevisiae under glucose limitation

Saccharomyces cerevisiae is a widely used cell factory; therefore, it is important to understand how it organizes key functional parts when cultured under different conditions. Here, we perform a multiomics analysis of S. cerevisiae by culturing the strain with a wide range of s...

2022-08-31 | MTBLS697 | MetaboLights
TranscriptomicsRNA-seq of yeast cell cycle, used for absolute gene expression quantification
We use Saccharomyces cerevisiae to perform absolute quantitative multi-omics analysis to map interactions of different cellular processes during the yeast cell cycle.
ORGANISM(S): Saccharomyces cerevisiae 
2020-03-30 | E-MTAB-8565 | biostudies-arrayexpress
ProteomicsYeast cell cycle proteome and phosphoproteome (LC-MSMS)
Multi-omic absolute quantitative analysis of the yeast (Saccharomyces cerevisiae) mitotic cell cycle. Transcriptomics (RNA-Seq), proteomics (SILAC/ iBAQ), phosphoproteomics (SILAC/ iBAQ, enrichment with TiO2), and untargeted metabolomics (Metabolon, Inc.) were performed, all in biological triplicate...
ORGANISM(S): Saccharomyces cerevisiae (Baker's yeast) 
2020-03-26 | PXD016519 | Pride
Lc-msms Budding yeast Multi-omics Mitosis Respiration Fermentation Ibaq Cell cycle Silca 
UnknownA tumor focused approach to resolving the etiology of DNA mismatch repair deficient tumors classified as suspected Lynch syndrome.
Not available
S-EPMC10134620 | biostudies-literature
UnknownImmunization with inactivated whole virus particle influenza virus vaccines improves the humoral response landscape in cynomolgus macaques.
Not available
S-EPMC9581423 | biostudies-literature
ProteomicsPatient induced pluripotent stem cells identify specificities of a reticular pseudodrusen phenotype in age-related macular degeneration
Age-related macular degeneration (AMD) is a leading cause of vision loss. Reticular pseudodrusen (RPD), deposits on the apical side of the retinal pigment epithelium (RPE), signify a distinctive and critical AMD phenotype. Yet, their molecular basis and relationship to the conventional drusen seen i...
ORGANISM(S): Homo sapiens (Human) 
2026-06-08 | PXD070797 | Pride
Human induced pluripotent stem cells  retinal pigment epithelium  single-cell rna sequencing  genome regulation  age-related macular degeneration  reticular pseudodrusen  transcriptomics  proteomics. 
TranscriptomicsTranscription profiling of mouse Atm-/-,mTerc-/-,p53-/- triple knock out lymphoma vs. normal mouse DNA (GPL2884)
Highly rearranged and mutated cancer genomes present major challenges in the identification of pathogenetic events driving the cancer process. Here, we engineered lymphoma-prone mice with chromosomal instability to assess the utility of mouse models in cancer gene discovery and the extent of cross-...
ORGANISM(S): Mus musculus 
2008-06-15 | E-GEOD-7600 | biostudies-arrayexpress
TranscriptomicsComparative genomic hybridization of human GBM tumor vs. normal human DNA induced in mice
Highly rearranged and mutated cancer genomes present major challenges in the identification of pathogenetic events driving the cancer process. Here, we engineered lymphoma-prone mice with chromosomal instability to assess the utility of mouse models in cancer gene discovery and the extent of cross-...
ORGANISM(S): Homo sapiens 
2008-06-15 | E-GEOD-7602 | biostudies-arrayexpress
TranscriptomicsComparative genomic hybridization (CGH) of human melanoma vs. normal human samples
Highly rearranged and mutated cancer genomes present major challenges in the identification of pathogenetic events driving the cancer process. Here, we engineered lymphoma-prone mice with chromosomal instability to assess the utility of mouse models in cancer gene discovery and the extent of cross-...
ORGANISM(S): Homo sapiens 
2008-06-15 | E-GEOD-7606 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human colon tumor vs normal DNA
Highly rearranged and mutated cancer genomes present major challenges in the identification of pathogenetic events driving the cancer process. Here, we engineered lymphoma-prone mice with chromosomal instability to assess the utility of mouse models in cancer gene discovery and the extent of cross-...
ORGANISM(S): Homo sapiens 
2008-06-15 | E-GEOD-7604 | biostudies-arrayexpress
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