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ProteomicsCharacterization of the acetylome associated with rapamycin-induced autophagy in HeLa cells
Autophagy is a lysosomal-mediated catabolic process that degrades cytoplasmic components to help maintain cellular homeostasis and cell survival during exposure to stress. Lysine acetylation is a reversible post-translational modification that plays an important role in the regulation of diverse cel...
ORGANISM(S): Homo sapiens (Human) 
2019-01-02 | PXD005793 | Pride
Autophagy  rapamycin  acetylome  acetylation  acetyltransferase 
ProteomicsIncorporation of isotopically labeled amino acids in live mouse zygotes as means to understand the oocyte to embryo transition
A long-standing question in developmental and reproductive biology is when the mammalian embryo becomes sufficiently distinct from its oocyte precursor. Myriads of studies examined the messenger RNAs that change during the oocyte-to-embryo transition, whereas proteins have been much less studied, in...
ORGANISM(S): Mus musculus (Mouse) 
2023-10-19 | PXD035570 | Pride
Blastocyst Proteomics Heavy amino acids Development Silac Mass spectrometry Oocyte Fertilization 
ProteomicsMus musculus primary CD4+ T cell di-glycine remnant and whole cell proteomics
It is known that ubiquitination is important for T cell receptor (TCR) signaling during T cell activation but the breadth of ubiquitination events triggered during TCR signaling is not completely understood. This dataset utilizes di-glycine remnant profiling combined with mass spectrometry to identi...
ORGANISM(S): Mus musculus (Mouse) 
2019-05-09 | PXD012831 | Pride
Mus musculus primary cd4+ t cell di-glycine remnant and whole cell proteomics 
ProteomicsYeast cell cycle proteome and phosphoproteome (LC-MSMS)
Multi-omic absolute quantitative analysis of the yeast (Saccharomyces cerevisiae) mitotic cell cycle. Transcriptomics (RNA-Seq), proteomics (SILAC/ iBAQ), phosphoproteomics (SILAC/ iBAQ, enrichment with TiO2), and untargeted metabolomics (Metabolon, Inc.) were performed, all in biological triplicate...
ORGANISM(S): Saccharomyces cerevisiae (Baker's yeast) 
2020-03-26 | PXD016519 | Pride
Lc-msms Budding yeast Multi-omics Mitosis Respiration Fermentation Ibaq Cell cycle Silca 
ProteomicsOvarian fluid proteome variation associates with sperm swimming speed in an externally fertilizing fish
Ovarian fluid was collected from 6 adult female Chinook salmon during their annual spawning run. Two replicates were analyzed for each ovarian fluid sample fraction using 80 and 100 minute gradients, respectively. Protein abundances were estimated using iTRAQ.
ORGANISM(S): Oncorhynchus tshawytscha 
2021-04-17 | PXD014551 | Pride
Oncorhynchus tshawytscha Chinook salmon Ovarian fluid Coelomic fluid Itraq 
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