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TranscriptomicsGenome-wide map of spliced-leader-led trans-splice sites in Oikopleura dioica
Polycistronic mRNAs transcribed from operons are resolved via the trans-splicing of a spliced leader (SL) RNA. The SL is also frequently trans-spliced to monocistronic transcripts. Using a modified cap analysis of gene expression (CAGE) protocol we mapped sites of SL trans-splicing genome-wide in th...
ORGANISM(S): Oikopleura dioica 
2015-01-26 | E-GEOD-50849 | biostudies-arrayexpress
TranscriptomicsHigh-resolution genome-wide transcriptomics analysis of O. dioica during recovery from growth arrest
Polycistronic mRNAs transcribed from operons are resolved via the trans-splicing of a spliced leader (SL) RNA. The SL is also frequently trans-spliced to monocistronic transcripts. Using a modified cap analysis of gene expression (CAGE) protocol we mapped sites of SL trans-splicing genome-wide in th...
ORGANISM(S): Oikopleura dioica 
2015-01-26 | E-GEOD-50848 | biostudies-arrayexpress
TranscriptomicsGenome-wide transcriptional responses to benzo[a]pyrene and clofibrate in the tunicate Oikopleura dioica
Animals have developed extensive mechanisms of response to xenobiotic chemical attacks. Although recent genome surveys have suggested a broad conservation of the chemical defensome across metazoans, global gene expression responses to xenobiotics are not known in most invertebrates. Here, using high...
ORGANISM(S): Oikopleura dioica 
2013-02-05 | E-GEOD-33818 | biostudies-arrayexpress
ProteomicsWDFY2 restrains matrix metalloproteinase secretion and cell invasion by controlling VAMP3-dependent recycling
The endosomal FYVE- and WD40-domain-containing protein WDFY2 has been assigned a function as tumor suppressor, but its functional mechanism has remained elusive. Here we have used confocal, widefield and super-resolution fluorescence microscopy to show that WDFY2 localizes to the base of retromer-co...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2019-07-23 | MSV000084122 | MassIVE
TranscriptomicsMicroarray-based comparison of RSC, Condensin and Cohesin
Total mRNA was isolated from parallel cultures of two Matalpha clones of each of the 7 temperature sensitive strains: STH1ts, SMC2ts, SMC3ts, STH1ts SMC2ts, STH1ts SMC3ts, SMC2ts SMC3ts, and STH1ts SMC2ts SMC3ts. The two biological replicates were processed in parallel and one was conjugated to Cy3,...
ORGANISM(S): Saccharomyces cerevisiae 
2006-12-31 | E-UMCU-21 | biostudies-arrayexpress
TranscriptomicsHigh-resolution genome-wide transcriptomics analysis of O. dioica development
The developmental transcriptomics of every significant developmental stage of O. dioica at ultra-high resolution. 18 samples were included, each in technical triplicate (and one with 4 replicates). These samples included 12 developmental time-point providing high-resolution interrogation of the comp...
ORGANISM(S): Oikopleura dioica 
2012-07-23 | E-GEOD-39568 | biostudies-arrayexpress
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