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GenomicsGenetics of Response to Canagliflozin
Genetics of Response to Canagliflozin
PRJNA1046216 | ENA
GenomicsGenetics of Response to Canagliflozin
Genetics of Response to Canagliflozin
PRJNA1046215 | ENA
ProteomicsCanagliflozin regulates ferroptosis to ameliorate heart failure in rats with preserved ejection fraction
Chronic heart failure (CHF), with whether reduced ejection fraction (HFrEF) or preserved ejection fraction (HFpEF), is the end-stage of various cardiovascular diseases and severely affects the patients’ lifespan. There has been no effective drugs to improve clinical outcomes for a long time. Sine th...
ORGANISM(S): Rattus norvegicus (Rat) 
2022-05-20 | PXD029031 | Pride
Sodium-glucose cotransporter 2 inhibitor Canagliflozin Heart failure Ferroptosis Lipid peroxidation 
GenomicsRNA-seq in gWAT from diabetic mice treated with canagliflozin
RNA-seq in gWAT from diabetic mice treated with canagliflozin
PRJNA1061139 | ENA
ProteomicsCanagliflozin Porcine Nonischemic Myocardium Raw Proteomics Data
Swine with chronic myocardial ischemia treated with canagliflozin (n=8) or control (n=8). Tissue harvested from nonischemic myocardium.
ORGANISM(S): Sus Scrofa Domesticus 
2023-08-24 | PXD044840 |
GenomicsThe effects of SGLT-2 inhibitors canagliflozin on hepatic transcription
The effects of SGLT-2 inhibitors canagliflozin on hepatic transcription
PRJNA471915 | ENA
GenomicsCanagliflozin impact on human renal proximal tubular cells (HK2)
Canagliflozin impact on human renal proximal tubular cells (HK2)
PRJNA415785 | ENA
GenomicsThe SGLT2 inhibitor canagliflozin suppresses growth and enhances prostate cancer response to radiotherapy
The SGLT2 inhibitor canagliflozin suppresses growth and enhances prostate cancer response to radiotherapy
PRJNA1000568 | ENA
TranscriptomicsRNA-seq in gWAT from diabetic mice treated with canagliflozin
We found canagliflozin shows elimination of senescent cells from organs in age-related pathology mouse model including diabetes. To clarify detailed change by canagliflozin treatement, we conducted RNA-seq analysis in gonadal white adipose tissue(gWAT).
ORGANISM(S): Mus musculus 
2024-04-06 | GSE252539 | GEO
TranscriptomicsThe SGLT2 inhibitor canagliflozin suppresses growth and enhances prostate cancer response to radiotherapy
Radiotherapy (RT) is a non-invasive standard treatment for prostate cancer (PC). However, PC develops radio-resistance, highlighting a need for agents to improve RT response. Canagliflozin, an inhibitor of sodium-glucose co-transporter-2, is approved for use in diabetes and heart failure, but is als...
ORGANISM(S): Homo sapiens 
2023-09-10 | GSE239688 | GEO
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