Cancer/testis antigens

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Lab affiliation

Institute for Research in Immunology and Cancer, Department of Biochemistry, Department of Chemistry, Université de Montréal, Québec, Canada H3T 1J4 (2)
The Institute of Cancer Research (2)
1. Department of Peptide-based Immunotherapy, Institute of Immunology, University and University Hospital Tübingen, Germany 2. Cluster of Excellence iFIT (EXC2180) “Image-Guided and Functionally Instructed Tumor Therapies”, University of Tübingen, Germany 3. Clinical Collaboration Unit Translational Immunology, Department of Internal Medicine, University Hospital Tübingen, Germany 4. German Cancer Consortium (DKTK) and German Cancer Research Center (DKFZ), partner site Tübingen, Germany (1)
Department of Biology, Technion - Israel Institute of Technology, Haifa, Israel (1)
Department of Biology, Technion – Israel Institute of Technology, Haifa, Israel (1)
Department of Biology, Technion–Israel Institute of Technology Haifa, Israel (1)
Department of Hematology and Oncology, University of Tübingen, Germany (1)
Department of Peptide-based Immunotherapy (1)
Faculty of Biology, Technion-Israel Institute of Technology, Haifa, Israel (1)
Head / Immunopeptidomics unit Department of Oncology UNIL/CHUV Ludwig Cancer Research Center Biopole III, Chemin des Boversses 155 Epalinges, 1066 Switzerland (1)
Head Proteomics Group Leiden University Medical Center |Center for Proteomic and Metabolomics | PO Box 9600 | Postal zone P1-Q | 2300 RC Leiden | The Netherlands (1)
Head of System Biology Lab. at Lopukhin Federal Research and Clinical Center of Physical-Chemical Medicine of Federal Medical Biological Agency (1)
Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology (1)
Senior Research Fellow Head, Male Fertility Regulation Laboratory (1)
Thoracic and GI Malignancies Branch, Center for Cancer Research, NCI, NIH, Bethesda, MD 20892 (1)
md anderson cancer center (1)

Location

Belgium (1)

Keyword

Hepatic arterial infusion (1)
Decitabine (1)

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Sperm-specific proteins and cancer testis antigens exist outside the blood-testis barrier

Sperm develop in the seminiferous tubules of the testis from puberty, sequestered inside the blood-testis barrier to prevent their recognition as “non-self” by the immune system. It is widely assumed that proteins expressed specifically in sperm do not have direct access to the circulation or the im...

ORGANISM(S): Homo sapiens (Human) Mus musculus (Mouse)

2021-04-01 | PXD014333 | Pride

Oncogenic cancer/testis antigens: prime candidates for immunotherapy.

Not available

S-EPMC4599236 | biostudies-literature

Cancer/testis (CT) antigens, carcinogenesis and spermatogenesis.

Not available

S-EPMC3271663 | biostudies-literature

Identification of tumor antigens among the HLA peptidomes of Glioblastoma tumors and plasma

Glioblastoma multiforme (GBM) is the most aggressive brain tumor with poor prognosis to most patients. Immunotherapy of GBM is a potentially beneficial treatment option, whose optimal implementation may depend on familiarity with tumor specific antigens, presented as HLA peptides by the GBM cells. F...

ORGANISM(S): Homo Sapiens (ncbitaxon:9606)

MSV000084343 | MassIVE

Cancer/testis antigens and urological malignancies.

Not available

S-EPMC3477645 | biostudies-literature

Histone H3.3K27M mutation activates multiple cancer/testis antigens

Lysine27Methionine mutations (K27M) in the histone H3 (H3.3 and H3.1) are highly prevalent in pediatric high-grade gliomas (HGG). This study found H3.3K27M caused the upregulation of multiple cancer/testis (CT) antigens, include IL13RA2 and VCX family proteins. Overexpression of VCX3A/B stimulates t...

ORGANISM(S): Homo sapiens

2018-08-01 | GSE102886 | GEO

Cancer/testis antigens: promising immunotherapy targets for digestive tract cancers.

Not available

S-EPMC10311965 | biostudies-literature

Single Cell lineage Tracing Identifies Cancer Testis Antigens as Mediators of Chemoresistance in Small Cell Lung Cancer

PRJNA892526 | ENA

In-depth proteomic profiling of gastric cancer tumor cells uncovers previously unidentified cancer testis antigens

ORGANISM(S): Homo sapiens (Human)

2024-06-06 | PXD047203 | Pride

[rptep Ocs

Biology of Cancer-Testis Antigens and Their Therapeutic Implications in Cancer.