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ProteomicsThe human milk oligosaccharide 2’-fucosyllactose protects against high-fat diet induced obesity by changing intestinal mucus production, composition and degradation linked to changes in gut microbiota and fecal proteome profiles in mice
The aim of this study was to decipher the mechanisms by which the major human milk oligosaccharide (HMO), 2’-fucosyllactose (2’FL), can affect body weight and fat mass gain upon high-fat diet (HFD) feeding in mice. In particular, we wanted to elucidate whether 2’FL metabolic effects are linked with ...
ORGANISM(S): Mus musculus (Mouse) Bacteria 
2025-05-06 | PXD049406 | Pride
Human milk oligosaccharides Obesity Gut barrier. Gut microbiota Mucus Fecal proteome Diabetes 
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