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TranscriptomicsIdentification of candidate susceptibility and resistance genes of mice infected with Streptococcus suis type 2
There were four groups:control A/J mice;control B6 mice;SS2-infected A/J mice;SS2-infected B6 mice.The RNA samples of four groups were sent to Biostar Genechip Inc. (Shanghai, China) for microarray hybridization. The pooled RNA sample from each group was hybridized to one Illumina mouse Genome Beadc...
ORGANISM(S): Mus Musculus 
2012-02-09 | E-MTAB-745 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of mouse A/J strain treated with cigarette smoke (CS) vs Air treated lungs
We hypothesize that gene expression in the CS-exposed lungs of this strain (A/J) of mice would be able to give clues about the molecular mechanism of emphysema development, thus contributing to this phenotype. More specifically, although imbalance in oxidants/antioxidants and proteinase/antiproteina...
ORGANISM(S): Mus musculus 
2009-03-28 | E-GEOD-8790 | biostudies-arrayexpress
GenomicsThe In Vivo Pattern of Binding of RAG1 and RAG2 to Antigen Receptor Loci
The critical initial step in V(D)J recombination, binding of RAG1 and RAG2 to recombination signal sequences flanking antigen receptor V, D, and J gene segments, has not previously been characterized in vivo. Here we demonstrate that RAG protein binding occurs in a highly focal manner to a small reg...
ORGANISM(S): Mus musculus 
2010-04-19 | E-GEOD-21207 | biostudies-arrayexpress
ProteomicsRBM39 organizes an m⁶A-dependent silencing complex to degrade Tat mRNA and maintain HIV-1 latency
Given the pivotal role of Tat in HIV-1 latency, we performed RNA pull-down assays in latently HIV-1-infected J-Lat 10.6 cells using biotinylated RNA probes (including a control RNA probe and a Tat-specific RNA probe) . Cell lysates were incubated with streptavidin agarose resin pre-bound to Tat RNA ...
ORGANISM(S): Homo sapiens (Human) 
2025-10-31 | PXD064834 | Pride
Lc/ms Tat Rip J-lat 10.6 
ProteomicsIn-depth serum proteomics of hospitalized COVID-19 patients and PCR-negative healthy controls with HiRIEF LC-MS/MS
We performed in-depth MS-based plasma-proteome profiling in 20 hospitalised patients with COVID-19 and 7 healthy controls (PCR- and sero-negative for SARS-CoV-2) by high-resolution isoelectric focusing (HiRIEF) coupled with liquid chromatography and mass-spectrometry (LC-MS/MS). The SARS‐CoV‐2 PCR‐c...
ORGANISM(S): Homo sapiens (Human) 
2023-09-01 | PXD037486 | Pride
Covid-19 Human Serum Plasma Sars-cov-2 Hirief Lc-ms/ms 
UnknownExosomal circRNA BTG2 derived from RBP-J overexpressed-macrophages inhibits glioma progression via miR-25-3p/PTEN.
Not available
S-EPMC9148311 | biostudies-literature
UnknownRapid detection of avian leukosis virus subgroup J by cross-priming amplification.
Not available
S-EPMC8155010 | biostudies-literature
UnknownA Novel Statin Compound from Monacolin J Produced Using CYP102A1-Catalyzed Regioselective C-Hydroxylation.
Not available
S-EPMC8541633 | biostudies-literature
UnknownKnockout of p53 leads to a significant increase in ALV-J replication.
Not available
S-EPMC8377548 | biostudies-literature
TranscriptomicsDietary folate depletion and repletion in A/J and C57BL/6J mice
Defects in homocysteine and folate metabolism are associated with increased risks for neural tube and congenital heart defects, cardiovascular disease and stroke, cancers, and neurodegeneration. In many but not all cases, dietary supplementation with folate significantly reduces the severity and in...
ORGANISM(S): Mus musculus 
2008-08-27 | E-GEOD-9242 | biostudies-arrayexpress
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