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ProteomicsPlasma proteome changes during the first week of human life in two independent cohorts
Introduction: Early life is characterized by heightened susceptibility to infections and is recognized as a major determinant of the immune system development and the overall health for the entire human lifespan. However, our knowledge of the development of the neonatal immune system is incomplete, ...
ORGANISM(S): Homo sapiens (Human) 
2020-11-24 | PXD019817 | Pride
Lc-ms Plasma Human Healthy Dda Newborn Ontogeny 
TranscriptomicsDevelopment of GRO-cap (GRO-seq followed by 5'-cap enrichment) to map transcription start sites in C. elegans
Dosage Compensation is required to correct for uneven gene dose between the sexes. We utilized global run-on sequencing (GRO-seq) to examine how Caenorhabditis elegans dosage compensation reduces transcription of X-linked genes. To facilitate these experiments, we required accurate 5M-bM-^@M-^Y-ends...
ORGANISM(S): Caenorhabditis elegans 
2013-06-18 | E-GEOD-43085 | biostudies-arrayexpress
TranscriptomicsUsing GRO-seq experiments to determine the mechanism of C. elegans dosage compensation's control of transcription
Dosage Compensation is required to correct for uneven gene dose between the sexes. We utilized global run-on sequencing (GRO-seq) to examine how Caenorhabditis elegans dosage compensation reduces transcription of X-linked genes. To facilitate these experiments, we required accurate 5M-bM-^@M-^Y-ends...
ORGANISM(S): Caenorhabditis elegans 
2013-06-18 | E-GEOD-43084 | biostudies-arrayexpress
TranscriptomicsMouse Soleus Muscle Chronic Electrical Stimulation Study
Stimulation of the mouse hindlimb via the sciatic nerve was used to induce contractions for 4 hours to investigate acute muscle gene activation in a model of muscle phenotype conversion. Initial force production (1.6 + 0.1 g/g body weight) declined 45% within 10 min and was maintained for the remain...
ORGANISM(S): Mus musculus 
2010-06-01 | E-GEOD-14391 | biostudies-arrayexpress
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