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TranscriptomicsAge-dependent changes in the gene expression profile of mice over-expressing mutant APP, PS1 and phosphorilated tau
In this study, using a microarray approach, we investigated the age-dependent changes in the gene expression profile of hippocampi obtained from young and old 3xTg-AD and WT control mice, in order to identify the molecular mechanisms involved in the development of AD and assess the role of aging in...
ORGANISM(S): Mus musculus 
2012-06-27 | E-GEOD-35210 | biostudies-arrayexpress
TranscriptomicsscRNAseq NOHA
To investigate the impact of hormonal modulation on neurodevelopmental processes, we performed single-cell RNA sequencing (ScRNA-seq) on neural organoids derived from two genetically validated human induced pluripotent stem cell (hiPSC) control lines (CTL08, male; CTL04, female). Organoids were chro...
ORGANISM(S): Homo sapiens 
2026-07-22 | E-MTAB-17184 | biostudies-arrayexpress
UnknownHuman Cortical Organoids Expose a Differential Function of GSK3 on Cortical Neurogenesis.
Not available
S-EPMC6893153 | biostudies-literature
GenomicsEMseq of hiPSC, iMeLC, hPGCLC and hEGCLC of CTL08A genotype
In this work, hEGCLC have been obtained for the first time from hPGCLC in defined and feeder-free conditions. To study epigenetic changes (in terms of DNA methylation) during the transition from a pluripotent stem cell state to a germ cell identity and back again, we profiled hiPSC, iMeLC, day 6 hPG...
ORGANISM(S): Homo sapiens 
2026-02-10 | E-MTAB-15142 | biostudies-arrayexpress
TranscriptomicsLow-pass WGS of hiPSC and hEGCLC samples of CTL08A genotype
Low-pass whole genome sequencing (WGS) of one sample of human induced pluripotent stem cells (hiPSCs) derived from the CTL08A male cell line and three samples of CTL08A human embryonic germ cell-like cells (hEGCLCs) at passage 10 after hPGCLC-hEGCLC conversion.
ORGANISM(S): Homo sapiens 
2026-02-10 | E-MTAB-15528 | biostudies-arrayexpress
Transcriptomicsbulk RNA-seq NOHA
Bulk RNA sequencing (bulk RNA-seq) data of the Neural Organoid Hormonal Atlas (NOHA). To investigate the impact of hormonal modulation on neurodevelopmental processes, we used neural organoids derived from two genetically validated human induced pluripotent stem cell (hiPSC) control lines (CTL08, ma...
ORGANISM(S): Homo sapiens 
2026-07-22 | E-MTAB-17185 | biostudies-arrayexpress
UnknownDownstream or upstream administration of P2Y12 receptor blockers in non-ST elevated acute coronary syndromes: study protocol for a randomized controlled trial.
Not available
S-EPMC7686679 | biostudies-literature
UnknownDiversity, functional classification and genotyping of SHV β-lactamases in Klebsiella pneumoniae.
Not available
S-EPMC11493186 | biostudies-literature
UnknownRisk profiles and one-year outcomes of patients with newly diagnosed atrial fibrillation in India: Insights from the GARFIELD-AF Registry.
Not available
S-EPMC6306365 | biostudies-literature
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