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ProteomicsReticular fibroblasts counteract radiotherapy-induced head and neck tumor regression through Tenascin-C
Head and neck squamous cell carcinoma (HNSCC) patients have a very short survival. To improve patient survival, there is an emerging need for a better understanding of the obstacles of ionizing irradiation (IR), besides surgery, currently the best treatment option for HNSCC. A confounding factor is ...
ORGANISM(S): Mus musculus (Mouse) 
2026-01-14 | PXD060164 | Pride
Tenascin-c Radiotherapy Reticular fibroblasts Tumor 
TranscriptomicsTenascin-C shapes TRAIL control over tumor immunity
TRAIL cytotoxicity is exploited as anti-cancer therapy since many years, however incomplete knowledge is generating many obstacles. Here, we address whether the highly abundant extracellular matrix molecule tenascin-C (TNC) orchestrating an immune suppressive tumor microenvironment and binding TRAIL...
ORGANISM(S): Mus musculus 
2024-05-30 | E-MTAB-14089 | biostudies-arrayexpress
ProteomicsTenascin-C shapes TRAIL control over tumor immunity
TRAIL cytotoxicity is exploited as anti-cancer therapy since many years, however incomplete knowledge is generating many obstacles. Here, we address whether the highly abundant extracellular matrix molecule tenascin-C (TNC) orchestrating an immune suppressive tumor microenvironment and binding TRAIL...
ORGANISM(S): Mus musculus (Mouse) 
2026-04-15 | PXD045388 | Pride
Shotgun proteomics Tenascin c Trail Maremo peptide mp5 
UnknownMapping rRNA 2'-O-methylations and identification of C/D snoRNAs in Arabidopsis thaliana plants.
Not available
S-EPMC8583080 | biostudies-literature
TranscriptomicsReticular fibroblasts counteract radiotherapy-induced head and neck tumor regression through Tenascin-C
Head and neck squamous cell carcinoma (HNSCC) patients have a very short survival. To improve patient survival, there is an emerging need for a better understanding of the obstacles of ionizing irradiation (IR), besides surgery, currently the best treatment option for HNSCC. A confounding factor is ...
ORGANISM(S): Mus musculus 
2025-02-14 | E-MTAB-14801 | biostudies-arrayexpress
UnknownTenascin-C immobilizes infiltrating T lymphocytes through CXCL12 promoting breast cancer progression.
Not available
S-EPMC8185552 | biostudies-literature
ProteomicsQuantitative proteomic profiling of Arabidopsis nuclei reveals accumulation of nucleolar proteins after a prolonged heat stress
Heat stress (HS) impacts the nuclear proteome and, subsequently, protein activities in the nucleoplasm and/or different nuclear compartments. In Arabidopsis thaliana, a short exposure to 37°C leads to the loss of the standard tripartite architecture of the nucleolus, the most prominent nuclear subst...
ORGANISM(S): Arabidopsis thaliana (Mouse-ear cress) 
2024-10-17 | PXD045038 | Pride
Nanolc-msms Heat stress Nucleolus Nucleus 
UnknownInvestigating Chemokine-Matrix Networks in Breast Cancer: Tenascin-C Sets the Tone for CCL2.
Not available
S-EPMC10179296 | biostudies-literature
ProteomicsN2-methylguanosine modifications on human tRNAs and snRNA U6 are important for colon cancer cell proliferation, protein translation and pre-mRNA splicing
Modified nucleotides in non-coding RNAs, such as tRNAs and snRNAs, represent an important layer of gene expression regulation through their ability to fine-tune mRNA maturation and transla-tion. Growing evidences support important roles of tRNA/snRNAs modifications and hence the enzymes that install...
ORGANISM(S): Homo sapiens (Human) 
2023-05-17 | PXD038967 | Pride
Ap-ms experiment 
UnknownImpact of Tenascin-C on Radiotherapy in a Novel Syngeneic Oral Squamous Cell Carcinoma Model With Spontaneous Dissemination to the Lymph Nodes.
Not available
S-EPMC8287883 | biostudies-literature
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