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MetabolomicsMetabolic Response of a Chemolithoautotrophic Archaeon to Carbon Limitation

The ubiquitously distributed ammonia-oxidizing archaea generate energy from ammonia and build cell mass from inorganic carbon sources, thereby contributing to both the global nitrogen and carbon cycles. However, little is known about the regulation of their predicted core carbon metabolism. A the...

2025-09-27 | MTBLS11689 | MetaboLights
MetabolomicsExometabolomic profiling of bacterial strains cultivated using Arabidopsis root extract as the sole carbon source
The ability of microorganisms to use root-derived metabolites as growth substrates is a key trait for success in the rhizospheric niche. However, few studies describe which specific metabolites are consumed, or to what degree microbial strains differ in their substrate consumption patterns. Here we ...
2018-10-16 | MTBLS555 | MetaboLights
MetabolomicsPhotosynthetic Carbon Partitioning and Metabolic Regulation in Response to Very-Low and High CO2 in Microchloropsis gaditana NIES 2587
Photosynthetic organisms fix inorganic carbon through carbon capture machinery (CCM) that regulates the assimilation and accumulation of carbon around ribulose-1,5-bisphosphate carboxylase/oxygenase (Rubisco). However, few constraints that govern the central carbon metabolism are regulated by the ca...
2022-01-14 | MTBLS1778 | MetaboLights
MetabolomicsHierarchical Carbon Metabolism in Iron-Deficient Bacteria Favors Iron-Scavenging Strategy

High-affinity iron (Fe) scavenging compounds, or siderophores, are widely employed by soil bacteria to survive scarcity in bioavailable Fe. Siderophore biosynthesis relies on cellular carbon metabolism, despite reported decrease in both carbon uptake and Fe-containing metabolic proteins in Fe-def...

2020-12-05 | MTBLS1715 | MetaboLights
MetabolomicsAn obligate aerobe adapts to hypoxia by hybridising fermentation with carbon storage
In soil ecosystems, obligately aerobic bacteria survive oxygen deprivation (hypoxia) by entering non-replicative persistent states. Little is known about how these bacteria rewire their metabolism to stay viable during persistence. The model obligate aerobe Mycobacterium smegmatis maintains redox ho...
2026-04-22 | MTBLS11404 | MetaboLights
MetabolomicsCharacterization of Phytoplankton-Excreted Metabolites Mediating Carbon Flux through the Surface Ocean

The marine labile dissolved organic carbon (DOC) pool is a dynamic reservoir of thousands of molecules. After excretion or release by phytoplankton and other microbes, metabolites are rapidly consumed, resulting in very low standing concentrations (picomolar to low nanomolar). To date, marine phy...

2026-03-17 | MTBLS12895 | MetaboLights
MetabolomicsComposition and consumption of dissolved organic carbon in seawater under sea ice

Polar regions are an under-studied environment within the global ocean, with seawater found under sea ice particularly under-sampled. This project provides concentrations of select dissolved organic carbon compounds found in under-ice seawater sampled between March and May 2023. The dissolved org...

2026-07-02 | MTBLS12381 | MetaboLights
TranscriptomicsAspergillus nidulans strains TNO2a3, M-bM-^HM-^FsnfA and M-bM-^HM-^FschA grown on avicel as sole carbon source
Transcriptome of A. nidulans TNO2a3, M-bM-^HM-^FsnfA and M-bM-^HM-^FschA strains when grown on complete media (CM) and transferred to minimal media plus avicel as a sole carbon source for 8 and 24 hours. Three conditions: complete media (reference) for 24h, and minimal media plus avicel for 8 and 24...
ORGANISM(S): Emericella nidulans 
2013-07-16 | E-GEOD-47810 | biostudies-arrayexpress
MetabolomicsPhotorespiration is linked to DNA methylation by formate as one-carbon source.
DNA methylation is a key epigenetic modification regulating genome organization, stability, and gene expression. Stable DNA methylation critically relies on methyl groups provided through folate-mediated one-carbon (C1) metabolism, yet the origin and regulation of C1 supply remain elusive. Here we d...
2026-01-06 | MTBLS13444 | MetaboLights
MetabolomicsRegulatory mechanisms for aromatic carbon metabolism in Comamonas testosteroni
Widely reported discrepancies between metabolic flux and transcripts or enzyme levels in bacterial metabolism imply complex regulation mechanisms need to be considered, especially in new bacterial platforms for bioremediation and bioproduction. Comamonas testosteroni strains, which metabolize variou...
2022-11-21 | MTBLS3947 | MetaboLights
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