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ProteomicsCard19 Iinteraction Partners in Murine Macrophages
The function of the mitochondrial protein CARD19 remains largely unknown. To begin to understand the molecular function of CARD19, we performed mass spectrometry-based proteomics to identify interacting partners of CARD19 in murine macrophages. We analyzed anti-MYC tag immunoprecipitates of 3xMYC-CA...
ORGANISM(S): Mus musculus (Mouse) 
2022-05-19 | PXD029157 | Pride
Micos C9orf89 Mtx2 Card19 Samm50 Mitochondria Chchd3 Bincard Immt Chchd6 
UnknownCARD19 Interacts with Mitochondrial Contact Site and Cristae Organizing System Constituent Proteins and Regulates Cristae Morphology.
Not available
S-EPMC8997538 | biostudies-literature
TranscriptomicsThe Card19 locus regulates apoptosis and pyroptosis downstream of caspase activation and gasdermin D cleavage independently from IL-1 cytokine release
Cell death plays a critical role in inflammatory responses. During pyroptosis, inflammatory caspases cleave Gasdermin D (GSDMD) to release an N-terminal fragment that generates plasma membrane pores that mediate cell lysis and IL-1 release. However, certain stimuli and cell types release IL-1 cytoki...
ORGANISM(S): Mus musculus 
2021-03-21 | GSE168489 | GEO
UnknownCARD19, the protein formerly known as BinCARD, is a mitochondrial protein that does not regulate Bcl10-dependent NF-κB activation after TCR engagement.
Not available
S-EPMC7484395 | biostudies-literature
UnknownGenetic targeting of Card19 is linked to disrupted NINJ1 expression, impaired cell lysis, and increased susceptibility to Yersinia infection.
Not available
S-EPMC8547626 | biostudies-literature
GenomicsThe Card19 locus regulates apoptosis and pyroptosis downstream of caspase activation and gasdermin D cleavage independently from IL-1 cytokine release
The Card19 locus regulates apoptosis and pyroptosis downstream of caspase activation and gasdermin D cleavage independently from IL-1 cytokine release
PRJNA707553 | ENA
UnknownA Bayesian network structure learning approach to identify genes associated with stress in spleens of chickens.
Not available
S-EPMC9076669 | biostudies-literature
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