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The differentiation to cardiomyocytes is a prerequisite and an important part of heart development. A good understanding of the complicated cardiomyocyte differentiation process benefits cardiogenesis study. Embryonic stem cells (ESCs), cell lines with infinite ability to proliferate and to be diffe...
ORGANISM(S): Mus musculus 

Background: Heart failure with reduced ejection fraction (HFrEF) is characterized by impaired contractility and high mortality. Dysregulation of intracellular ion cycling underlies the decline in cardiac contractility. Modulation of cardiac Na+/H+ and Ca2+ handling is consider...

2026-02-20 | MTBLS13690 | MetaboLights

Background: Heart failure with reduced ejection fraction (HFrEF) is characterized by impaired contractility and high mortality. Dysregulation of intracellular ion cycling underlies the decline in cardiac contractility. Modulation of cardiac Na+/H+ and Ca2+ handling is consider...

2026-02-20 | MTBLS13696 | MetaboLights
In this study, we investigated the effects of ethanol exposure on cardiomyocyte differentiation by treating the cells with various concentrations of ethanol. The results indicated that ethanol exposure during hiPSC-CM differentiation reduced cell viability, cell proliferation, and cardiomyocyte yiel...
ORGANISM(S): Homo sapiens (Human) 
2025-05-23 | PXD056092 | Pride
The transition from progenitor to differentiated cells is critical for successful organogenesis; subtle alterations in this process can lead to developmental disorders. The anterior heart field (AHF) encompasses a niche in which cardiac progenitors maintain their multipotent and undifferentiated nat...
ORGANISM(S): Gallus gallus 
Parallel transcription profiling of cardiomyocyte clusters derived from human embryonic stem cells. Both mRNA (this experiment) and miRNA (see E-MEXP-2655) transcription are measured and fetal and adult heart tissues are included as controls. This experiment was updated on 7th July 2011 to fix incor...
ORGANISM(S): Homo sapiens 
MiR-31 regulation of human cardiomyocyte differentiation
Parallel transcription profiling of cardiomyocyte clusters derived from human embryonic stem cells. Both mRNA (E-MEXP-2654) and miRNA (this experiment) transcription are measured and fetal and adult heart tissues are included as controls. This experiment was updated on 7th July 2011 to fix incorrect...
ORGANISM(S): Homo sapiens 
The rat cardio-myoblast cell line H9C2 has emerged as an important tool for studying cardiac development and toxicology. We present here a rigorous proteomic analysis that for the first time studied changes of proteins during H9C2 differentiation into cardiomyocyte-like cells over time. Quantitative...
ORGANISM(S): Rattus norvegicus (Rat) 
2018-11-07 | PXD006115 | Pride
RNA sequencing for human induced pluripotent stem cell cardiomyocyte differentiation
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