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UnknownClinical governance of patients with acute coronary syndromes.
Not available
S-EPMC9709629 | biostudies-literature
GenomicsGenomic and Proteomic Analyses of Prdm5 Reveal Interactions with Insulator Binding Proteins in Embryonic Stem Cells (ChIP-seq)
PRDM proteins belong to the SET domain protein family, which is involved in the regulation of gene expression. Although few PRDM members possess histone methyltransferase activity, the molecular mechanisms by which the other members exert transcriptional regulation remain to be delineated. In this s...
ORGANISM(S): Mus musculus 
2013-10-31 | E-GEOD-51816 | biostudies-arrayexpress
TranscriptomicsGenomic and Proteomic Analyses of Prdm5 Reveal Interactions with Insulator Binding Proteins in Embryonic Stem Cells (RNA-seq)
PRDM proteins belong to the SET domain protein family, which is involved in the regulation of gene expression. Although few PRDM members possess histone methyltransferase activity, the molecular mechanisms by which the other members exert transcriptional regulation remain to be delineated. In this s...
ORGANISM(S): Mus musculus 
2013-10-31 | E-GEOD-51553 | biostudies-arrayexpress
TranscriptomicsPrdm5 suppresses ApcMin-driven intestinal adenomas and regulates monoacylglycerol lipase expression
PRDM proteins are tissue specific transcription factors often deregulated in diseases, particularly in cancer where different members have been found to act as oncogenes or tumor suppressors. PRDM5 is a poorly characterized member of the PRDM family for which several studies have reported a high fre...
ORGANISM(S): Mus musculus 
2013-05-11 | E-GEOD-46821 | biostudies-arrayexpress
UnknownA validation study of a new classification algorithm to identify rheumatoid arthritis using administrative health databases: case-control and cohort diagnostic accuracy studies. Results from the RECord linkage On Rheumatic Diseases study of the Italian Society for Rheumatology.
Not available
S-EPMC4316439 | biostudies-literature
UnknownOutcomes predictors in endoscopic ultrasound-guided choledochoduodenostomy with lumen-apposing metal stent: Systematic review and meta-analysis.
Not available
S-EPMC10978093 | biostudies-literature
TranscriptomicsAlternative splicing detection workflow needs a careful combination of sample prep and bioinformatics analysis
Different Library Sample Preparation (LSP) allow the detection of a large common set of isoforms. However, each LSP also detects a smaller set of isoforms which are characterized both by lower coverage and lower FPKM than that observed for the common ones among LSPs. This characteristic is particula...
ORGANISM(S): Mus musculus 
2014-05-28 | E-GEOD-58001 | biostudies-arrayexpress
GenomicsThe Hippo tranducer YAP1 transforms activated satellite cells and is a potent effector of embryonal rhabdomyosarcoma formation
The Hippo pathway effector YAP1 controls stem cell fate in epithelial tissues, but its role in stem cells of non-epithelial tissues, such as skeletal muscle, is poorly documented. Here we show that sustained YAP1 activity in mouse activated satellite cells in vivo induces rhabdomyosarcoma (RMS) rese...
ORGANISM(S): Homo sapiens 
2014-08-12 | E-GEOD-55186 | biostudies-arrayexpress
UnknownDevelopment and First Validation of a Disease Activity Score for Gout.
Not available
S-EPMC5129490 | biostudies-literature
TranscriptomicsCharacterization of the genetic mouse model of non-small cells lung cancer p53R172HM-bM-^HM-^Fg/KrasG12D
Background: Non-small cell lung cancer (NSCLC) accounts for 81% of all cases of lung cancer and they are often fatal because 60% of the patients are diagnosed at an advanced stage. Besides the need for earlier diagnosis, there is a great need for additional effective therapies. In this work we inves...
ORGANISM(S): Mus musculus 
2013-09-25 | E-GEOD-51144 | biostudies-arrayexpress
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