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GenomicsBPTF is required for c-MYC-induced remodelling of target chromatin and transcriptional activation
This SuperSeries is composed of the SubSeries listed below. Refer to individual Series
ORGANISM(S): Homo sapiens 
2016-01-19 | E-GEOD-65546 | biostudies-arrayexpress
Genomics5-hydroxymethylcytosine: the sixth DNA base
We performed a meta analysis of publicly available TET1, 5mC, 5hmC and genome wide bisulfite profiling data mostly from mouse embryonic stem cells (ESC). Genome wide chromatin immunoprecipitation combined with deep sequencing (ChIP-seq) has revealed binding of the TET1 protein at CpG-island (CGI) pr...
ORGANISM(S): Mus musculus 
2011-11-24 | E-GEOD-31343 | biostudies-arrayexpress
GenomicsBPTF is required for c-MYC-induced remodelling of target chromatin and transcriptional activation [ChIP-Seq]
The c-MYC oncogene is a key transcription factor deregulated in most human tumors. Histone marks associated with transcriptionally active genes in euchromatic islands define the set of high-affinity c-MYC targets. The mechanisms involved in their recognition by c-MYC are not known but likely involve...
ORGANISM(S): Homo sapiens 
2016-01-19 | E-GEOD-65544 | biostudies-arrayexpress
TranscriptomicsThe UBC-40 Urothelial Bladder Cancer Cell Line Index
This SuperSeries is composed of the SubSeries listed below. Refer to individual Series
ORGANISM(S): Homo sapiens 
2015-06-19 | E-GEOD-64573 | biostudies-arrayexpress
GenomicsGenome-wide map of GATA6 DNA binding in human PDAC cells
By studying a mouse model, as well as human tumors samples and cell lines, we have revealed a tumor suppressive role for Gata6 in the pathogenesis of pancreatic ductal adenocarcinoma (PDAC). In order to understand the mechanism underlying such tumor suppressive function, we analyzed the genome-wide ...
ORGANISM(S): Homo sapiens 
2015-02-03 | E-GEOD-47535 | biostudies-arrayexpress
TranscriptomicsBPTF is required for c-MYC-induced remodelling of target chromatin and transcriptional activation [RNA-Seq]
The c-MYC oncogene is a key transcription factor deregulated in most human tumors. Histone marks associated with transcriptionally active genes in euchromatic islands define the set of high-affinity c-MYC targets. The mechanisms involved in their recognition by c-MYC are not known but likely involve...
ORGANISM(S): Homo sapiens 
2016-01-19 | E-GEOD-65545 | biostudies-arrayexpress
GenomicsGenome wide profiling of PAX8 binding stes in PCCL3 rat cells
Analysis of PAX8 binding sites by chromatin immunoprecipitation coupled with ultra-high-throughput sequencing (ChIP-seq) in PCCL3 rat cells. Results provide insight into the contribution of this regulatory factor to transcription genome-wide. We generate a genome wide map of PAX8 binding sites in PC...
ORGANISM(S): Rattus norvegicus 
2012-06-27 | E-GEOD-26871 | biostudies-arrayexpress
TranscriptomicsGlobal gene expression in the adult Gata6 null mouse pancreas
We report the global gene expression of mouse pancreatic cells in a pancreas-specific conditional knock-out mouse for Gata6, as compared with age-matched controls. Total RNA was extracted from the pancreas of 6-8 -week old mice of the two genotypes and analyzed. at this age, Gata6P-/- pancreata are ...
ORGANISM(S): Mus musculus 
2015-02-03 | E-GEOD-47536 | biostudies-arrayexpress
GenomicsGata6
This SuperSeries is composed of the SubSeries listed below. Refer to individual Series
ORGANISM(S): Homo sapiens 
2015-02-03 | E-GEOD-47537 | biostudies-arrayexpress
TranscriptomicsRecurrent inactivation of STAG2 in bladder cancer is not associated with aneuploidy
This SuperSeries is composed of the SubSeries listed below. Refer to individual Series
ORGANISM(S): Homo sapiens 
2013-10-24 | E-GEOD-51641 | biostudies-arrayexpress
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