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GenomicsBPTF is required for c-MYC-induced remodelling of target chromatin and transcriptional activation
This SuperSeries is composed of the SubSeries listed below. Refer to individual Series
ORGANISM(S): Homo sapiens 
2016-01-19 | E-GEOD-65546 | biostudies-arrayexpress
Genomics5-hydroxymethylcytosine: the sixth DNA base
We performed a meta analysis of publicly available TET1, 5mC, 5hmC and genome wide bisulfite profiling data mostly from mouse embryonic stem cells (ESC). Genome wide chromatin immunoprecipitation combined with deep sequencing (ChIP-seq) has revealed binding of the TET1 protein at CpG-island (CGI) pr...
ORGANISM(S): Mus musculus 
2011-11-24 | E-GEOD-31343 | biostudies-arrayexpress
TranscriptomicsThe UBC-40 Urothelial Bladder Cancer Cell Line Index
This SuperSeries is composed of the SubSeries listed below. Refer to individual Series
ORGANISM(S): Homo sapiens 
2015-06-19 | E-GEOD-64573 | biostudies-arrayexpress
GenomicsBPTF is required for c-MYC-induced remodelling of target chromatin and transcriptional activation [ChIP-Seq]
The c-MYC oncogene is a key transcription factor deregulated in most human tumors. Histone marks associated with transcriptionally active genes in euchromatic islands define the set of high-affinity c-MYC targets. The mechanisms involved in their recognition by c-MYC are not known but likely involve...
ORGANISM(S): Homo sapiens 
2016-01-19 | E-GEOD-65544 | biostudies-arrayexpress
TranscriptomicsBPTF is required for c-MYC-induced remodelling of target chromatin and transcriptional activation [RNA-Seq]
The c-MYC oncogene is a key transcription factor deregulated in most human tumors. Histone marks associated with transcriptionally active genes in euchromatic islands define the set of high-affinity c-MYC targets. The mechanisms involved in their recognition by c-MYC are not known but likely involve...
ORGANISM(S): Homo sapiens 
2016-01-19 | E-GEOD-65545 | biostudies-arrayexpress
TranscriptomicsRecurrent inactivation of STAG2 in bladder cancer is not associated with aneuploidy
This SuperSeries is composed of the SubSeries listed below. Refer to individual Series
ORGANISM(S): Homo sapiens 
2013-10-24 | E-GEOD-51641 | biostudies-arrayexpress
GenomicsGenome wide profiling of PAX8 binding stes in PCCL3 rat cells
Analysis of PAX8 binding sites by chromatin immunoprecipitation coupled with ultra-high-throughput sequencing (ChIP-seq) in PCCL3 rat cells. Results provide insight into the contribution of this regulatory factor to transcription genome-wide. We generate a genome wide map of PAX8 binding sites in PC...
ORGANISM(S): Rattus norvegicus 
2012-06-27 | E-GEOD-26871 | biostudies-arrayexpress
TranscriptomicsThe UBC-40 Urothelial Bladder Cancer Cell Line Index [copy number variation]
This is a comprehensive genomic characterization of 40 urothelial bladder carcinoma (UBC) cell lines including information on origin, mutation status of genes implicated in bladder cancer (FGFR3, PIK3CA, TP53, and RAS), copy number alterations assessed using high density SNP arrays, uniparental diso...
ORGANISM(S): Homo sapiens 
2015-06-19 | E-GEOD-64572 | biostudies-arrayexpress
TranscriptomicsThe UBC-40 Urothelial Bladder Cancer Cell Line Index [gene expression]
This is a comprehensive genomic characterization of 40 urothelial bladder carcinoma (UBC) cell lines including information on origin, mutation status of genes implicated in bladder cancer (FGFR3, PIK3CA, TP53, and RAS), copy number alterations assessed using high density SNP arrays, uniparental diso...
ORGANISM(S): Homo sapiens 
2015-06-19 | E-GEOD-64279 | biostudies-arrayexpress
GenomicsGenome-wide map of GATA6 DNA binding in human PDAC cells
By studying a mouse model, as well as human tumors samples and cell lines, we have revealed a tumor suppressive role for Gata6 in the pathogenesis of pancreatic ductal adenocarcinoma (PDAC). In order to understand the mechanism underlying such tumor suppressive function, we analyzed the genome-wide ...
ORGANISM(S): Homo sapiens 
2015-02-03 | E-GEOD-47535 | biostudies-arrayexpress
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