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TranscriptomicsTranscription profiling to ompare the effects of Vitamin D3 treatment of mouse bone marrow derived dendritic cells with control, untreated cells, and additional effects of maturation of either treated or control cells with LPS
This experiment is designed to compare the effects of Vitamin D3 treatment of mouse bone marrow derived dendritic cells with control, untreated cells, and additional effects of maturation of either treated or control cells with LPS.
ORGANISM(S): Mus musculus 
2006-11-01 | E-MEXP-506 | biostudies-arrayexpress
TranscriptomicsComparative genomic hybridization of Clostridium sporogenes and Clostridium botulinum strains
Clostridium botulinum is a heterogeneous Gram-positive species that comprises four genetically and physiologically distinct groups of bacteria that share the ability to produce botulinum neurotoxin, the most poisonous toxin known to man, and the causative agent of botulism, a severe disease of human...
ORGANISM(S): Clostridium botulinum 
2007-05-23 | E-TABM-264 | biostudies-arrayexpress
TranscriptomicsGene expression in pancreatic ductal adenocarcinoma
To further develop our understanding of the gene expression signature of pancreatic ductal adenocarcinoma Gene expression signatures in macrodissected resected pancreatic ductal adenocarcinoma specimens
ORGANISM(S): Homo sapiens 
2014-03-14 | E-GEOD-55643 | biostudies-arrayexpress
TranscriptomicsPositioning of Necrotic Lobular Intraepithelial Neoplasias within the sequence of breast carcinoma progression
Lobular intraepithelial neoplasia grade 3 (LIN) is a recently recognized variant of intraepithelial lobular neoplasia of the breast composed of either uniform, generally small, cells (classic) with massive lobular distension, pleomorphic cells, signet-ring cells, or any cell type with necrosis. In ...
ORGANISM(S): Homo sapiens 
2010-06-20 | E-GEOD-14803 | biostudies-arrayexpress
TranscriptomicsArray comparative genomic hybridization analysis of flat epithelial atypia (DIN1a) and lobular intraepithelial neoplasia
Low grade flat ductal intraepithelial neoplasia (DIN1a, flat epithelial atypia) is one of the earliest morphologically recognizable neoplastic lesions of the breast. Frequently, it occurs in association with lobular intraepithelial neoplasia (LIN). The aim of this study was to elucidate chromosomal ...
ORGANISM(S): Homo sapiens 
2010-05-05 | E-GEOD-18187 | biostudies-arrayexpress
TranscriptomicsMethylation profiling of human first and thrid trimester placenta and whole blood
Fifteen DNA methylation array experiments were performed on five human chromosome specific array platforms (NimbleGen: HG18_CHR13_FT, HG18_CHR18_FT, HG18_CHR21_FT, HG18_CHRX_FT, HG18_CHRY_FT), comparing: (1) one female whole blood immunoprecipitated DNA fragments to their input DNA, (2) one 1st tri...
ORGANISM(S): Homo sapiens 
2009-05-01 | E-TABM-507 | biostudies-arrayexpress
TranscriptomicsChromatin immunoprecipitation of human lymphoblastic cell line GM06990 using anti Histone H3K4me1, H3K4me2, H3K4me3, H3ac and H4ac antibodies using an ENCODE array
ENCODE ChIP/chip study using lymphoblastic cell line GM06990 and anti Histone H3K4me1, H3K4me2, H3K4me3, H3ac and H4ac antibodies.
ORGANISM(S): Homo sapiens 
2005-06-13 | E-MEXP-269 | biostudies-arrayexpress
TranscriptomicsIllumina microarray analysis of brain regions following acute exposure to bilirubin or LPS
We developed a novel mouse model of acute bilirubin toxicity. 450mg/kg bilirubin was administered IP to mice, which exhibited transient hearing deficits and ataxia at 4 hours, and recovered by 24 hours. This toxicity is consistent with the human symptoms of bilirubin toxicity. To investigate the mol...
ORGANISM(S): Mus musculus 
2018-08-26 | E-MTAB-7102 | biostudies-arrayexpress
no omics definedTranscription profiling of mouse hemopoietic cell types at diferent stages of differentiation, focussing on regulatory T cells and tolerogenic dendritic cell subsets to compare microarray generated gene expression signals with gene expression tag frequencies generated by SAGE analysis
This experiment was designed to compare gene expression across a wide range of hemopoietic cell types at diferent stages of differentiation, focussing on regulatory T cells and tolerogenic dendritic cell subsets.
ORGANISM(S): none 
2008-01-12 | E-MEXP-845 | biostudies-arrayexpress
TranscriptomicsChromatin immunoprecipitation of human erythroleukemia cell line K-562 with H3K4me2, H3K4me3, H3ac, H4ac, Histone H2B and Histone H3 antibodies using an ENCODE array
ENCODE ChIP-chip study using human myelogenous leukemia cell line K-562 and anti histone H3K4me2 (Abcam; ab7766); H3K4me3 (Abcam; ab8580); H3ac (Upstate; 06-599); H4ac (Upstate; 06-866); Histone H2B (Abcam: ab1790) and Histone H3 (Abcam: ab1791) antibodies. Each antibody experiment was conducted in ...
ORGANISM(S): Homo sapiens 
2006-09-01 | E-TABM-140 | biostudies-arrayexpress
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