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ProteomicsThe transmembrane IL-15 isoform expressed on human melanoma cells triggers modulatory effects on tumor progression upon stimulation with the soluble IL-15R chain
Interleukin-15 (IL-15) is expressed in various cancers, including melanoma, where it exists in distinct membrane-associated isoforms. Primary melanoma cells predominantly express the non-cleavable transmembrane form (tmbIL-15), while metastatic cells also express a cleavable membrane-bound f...
ORGANISM(S): Homo sapiens (Human) 
2026-05-25 | PXD076097 | Pride
Il15 Cytokine Il15rα Skin cancer (melanoma) Natural killer (nk) cells 
ProteomicsIn vitro expanded and activated polyclonal γδ memory T cells for treatment of cancer
γδ-T lymphocytes are cells of the innate immune system exerting potent natural cytotoxicity against bacteria, viruses and tumours. This ability, coupled with their negligible alloreactivity, makes them attractive for adoptive immunotherapy approaches. To achieve a cell product suitable for clinical ...
ORGANISM(S): Homo sapiens (Human) 
2019-11-18 | PXD015506 | Pride
Γδ t cells cancer 
UnknownBevacizumab-mediated tumor vasculature remodelling improves tumor infiltration and antitumor efficacy of GD2-CAR T cells in a human neuroblastoma preclinical model.
Not available
S-EPMC5739560 | biostudies-literature
UnknownCraniofacial dysmorphogenesis including cleft palate in mice with an insertional mutation in the discs large gene.
Not available
S-EPMC86693 | biostudies-literature
ProteomicsSepiadarium austrinum Slime MSMS
Sepiadarium austrinum, the southern bottletail squid, is a small squid that inhabits soft sediments along Australia’s south-east coast. When provoked this squid rapidly secretes large volumes of slime as a defense mechanism. Behavioral observations suggest that this slime may be toxic to crabs but i...
ORGANISM(S): Sepiadarium austrinum 
2016-08-08 | PXD003207 | Pride
Squid Slime Orbitrap Cephalopod 
Transcriptomics10.5dpc Metanephric Mesenchyme V Intermediate Mesoderm
10.5dpc Metanephric Mesenchyme V Intermediate Mesoderm
ORGANISM(S): Mus musculus 
2010-06-09 | E-GEOD-2301 | biostudies-arrayexpress
UnknownDetecting communicative intent in a computerised test of joint attention.
Not available
S-EPMC5244879 | biostudies-literature
TranscriptomicsKidney development time course
Array Design; Mouse Compugen 22K Spotted Oligo Author; Sean Grimmond Common Reference (Yes/No, ID); Yes Mouse universal Reference (Stratagene) Concentration; 100 Data processing/normalization; Lowess Normalisation GeneSpring) Developmental Stage; embryonic Diseased/Normal; normal Dye Swap; red/green...
ORGANISM(S): Mus musculus 
2010-06-09 | E-GEOD-2282 | biostudies-arrayexpress
Transcriptomics15.5dpc Ureteric tree cells Vs rest
Triplicate pairwise comparsion of FACS sorted GFP+ve Vs GFP-ve cells from the kidneys of the HoxB7-GFP transgenic mice on compugen 22K mouse arrays. HoxB7-GFP mice express GFP in the ureteric tree and its derivatives while the metanephric mesenchyme, interstitium, developing vasculature etc do not.
ORGANISM(S): Mus musculus 
2010-06-09 | E-GEOD-2281 | biostudies-arrayexpress
Transcriptomics11.5dpc metanephroi V 13.5dpc fetal kidney
Direct comparison of dissected pools of 11.5dpc metanephroi V 13.5dpc fetal kidneys.
ORGANISM(S): Mus musculus 
2010-06-09 | E-GEOD-2285 | biostudies-arrayexpress
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