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GenomicsIL15 in treatment of rhesus macaques
IL15 in treatment of rhesus macaques
PRJNA677980 | ENA
GenomicsIL15 Deficiency in Rats
IL15 Deficiency in Rats
PRJNA893659 | ENA
TranscriptomicsRunx3 function in splenic NK cells activated in vivo by IL-15.
NK cells are innate immune cells that recognize and kill foreign, virally-infected and tumor cells without the need for prior immunization. NK expansion following viral infection is IL-2 or IL-15-dependent. To identify Runx3 regulated genes, NK cells were isolated from spleen of IL15/Ra injected WT...
ORGANISM(S): Mus musculus 
2014-01-22 | E-GEOD-50120 | biostudies-arrayexpress
TranscriptomicsIL15 in treatment of rhesus macaques
Rhesus macaques vaccinated by rhesus cytomegalovirus vectors expressing simian immunodeficiency virus proteins (RhCMV/SIV) activate gene expression signature associated with IL15. To examine the gene expression signature activated by IL15, we performed longitudinal examinations of rhesus macaques du...
ORGANISM(S): Macaca mulatta 
2021-06-28 | GSE160577 | GEO
TranscriptomicsIL15 Deficiency in Rats
NK cells are a major immune cell in the uterus during pregnancy. IL15 is required for the maturation of these cells, therefore a mutation in the IL15 gene results in a lack of NK cells. In this study, implantation sites were collected from gestational day 9.5 pregnant IL15 deficient or WT Sprague-Da...
ORGANISM(S): Rattus Rattus norvegicus 
2023-04-12 | GSE216395 | GEO
GenomicsRNA-seq identifies IL15-induced adipogenesis and fatty acid metabolism pathways in human adipocytes
RNA-seq identifies IL15-induced adipogenesis and fatty acid metabolism pathways in human adipocytes
PRJNA864769 | ENA
UnknownMyxoma virus expressing a fusion protein of interleukin-15 (IL15) and IL15 receptor alpha has enhanced antitumor activity.
Not available
S-EPMC4199602 | biostudies-literature
TranscriptomicsRNA-seq identifies IL15-induced adipogenesis and fatty acid metabolism pathways in human adipocytes
IL15 has been suggested to reduce WAT mass in obese mice models. However, the underlying molecular mechanism is largely unknown. We determined the gene expression profile of human adipocytes treated with vehicle or IL15. Adipocytes isolated from healthy donors exhibited reduced expression of gene si...
ORGANISM(S): Homo sapiens 
2022-08-03 | GSE210203 | GEO
UnknownRadiotherapy Cooperates with IL15 to Induce Antitumor Immune Responses.
Not available
S-EPMC7415682 | biostudies-literature
UnknownA novel multimeric IL15/IL15Rα-Fc complex to enhance cancer immunotherapy.
Not available
S-EPMC7954438 | biostudies-literature
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