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MetabolomicsThe pyruvate kinase, a metabolic sensor powering glycolysis, drives the metabolic control of DNA replication

BACKGROUND: In all living organisms, DNA replication is exquisitely regulated in a wide range of growth conditions to achieve timely and accurate genome duplication prior to cell division. Failures in this regulation cause DNA damage with potentially disastrous consequences ...

2022-04-19 | MTBLS4415 | MetaboLights
GenomicsIdentification of a novel Bromodomain / Casein Kinase II / TAF-containing complex as a regulator of mitotic condensin function
ABSTRACT: Condensin is a central regulator of mitotic genome structure, with mutants showing poorly condensed chromosomes and profound segregation defects. Here we identify the fission yeast NCT complex, comprising the Nrc1 BET-family tandem bromodomain protein (SPAC631.02), Casein Kinase II (CKII) ...
ORGANISM(S): Schizosaccharomyces pombe 
2014-01-10 | E-GEOD-53955 | biostudies-arrayexpress
TranscriptomicsMonopolar attachment of sister kinetochores at meiosis I requires casein kinase 1.
The segregation of maternal centromeres away from the paternal ones during the first division of meiosis depends on the attachment of sister kinetochores to microtubules emanating from the same spindle pole. In budding yeast monopolar attachment requires the recruitment to kinetochores of a protein ...
ORGANISM(S): Saccharomyces cerevisiae 
2010-06-10 | E-GEOD-4792 | biostudies-arrayexpress
ProteomicsFACT, PAF-C, and CKII
Protein-protein interaction analysis for RNA Polymerase II and its elongation factors including: the PAF Complex, the FACT Complex, casein kinase II, DSIF, and TFIIF. These studies also characterized a number of casein kinase II phosphorylation sites on the subunits of the PAF Complex.
ORGANISM(S): Saccharomyces Cerevisiae (ncbitaxon:4932) 
2015-07-20 | MSV000079197 | MassIVE
Proteomics29RNP kinase - Identification and characterization of chloroplast casein kinase II from Oryza sativa (rice)
We firstly identified a chloroplast casein kinase 2 from rice heparin sepharose enrichmen which could phosphorylate the RNP29. Then we identified the phosphorylation site of RNP29. We also performed the phosophoproteome analysis of rice and compared the phosphorylation site between rice and arabi...
ORGANISM(S): Oryza sativa (Rice) 
2015-04-27 | PXD001168 | Pride
Oryza sativa Chloroplast Casein kinase 2 
ProteomicsData-Independent Acquisition-Based global phosphoproteomics reveals diverse roles of AELs (Arabidopsis EL1-like) Casein kinase 1 in plant development
Casein kinase 1 (CK1) is a highly conserved and ubiquitous serine/threonine protein kinase in eukaryotic cells. AELs (Arabidopsis EL1-like) are plant-specific CK1s and function in a wide range of physiological and signaling processes. To comprehensively understand the cellular functions and regulato...
ORGANISM(S): Arabidopsis Thaliana 
2022-07-05 | PXD035098 |
GenomicsCasein Kinase II Phosphorylation of Spt6 Enforces Transcriptional Fidelity by Maintaining Spn1-Spt6 Interaction
Casein Kinase II Phosphorylation of Spt6 Enforces Transcriptional Fidelity by Maintaining Spn1-Spt6 Interaction
PRJNA505786 | ENA
ProteomicsDishevelled-3 protein conformation dynamics analyzed by FRET-based biosensors reveals a key role of casein kinase 1
Dishevelled (DVL) is the key component of the Wnt signaling pathway. Currently, DVL conformational dynamics under native conditions is unknown. To overcome this limitation, we developed the Fluorescein Arsenical Hairpin Binder- (FlAsH-) based FRET in vivo approach to study DVL conformation in living...
ORGANISM(S): Homo sapiens (Human) 
2019-04-02 | PXD013085 | Pride
Dishevelled Casein kinase 1 ɛ Conformation Phosphorylation Flash-based fret approach 
GenomicsCasein kinase 1 and 2 phosphorylate Argonaute proteins to regulate miRNA-mediated gene silencing
Casein kinase 1 and 2 phosphorylate Argonaute proteins to regulate miRNA-mediated gene silencing
PRJNA999321 | ENA
Proteomics29RNP kinase idetification - Identification and characterization of chloroplast casein kinase II from Oryza sativa (rice)
The 29-kDa RNA protein (29RNP), which was originally identified in rice etioplasts, has increased phosphorylation levels during de-etiolation. Here, using heparin-sepharose enriched fractions, we identified a chloroplast kinase that phosphorylated 29RNP. The chloroplast kinase phosphorylated the 29R...
ORGANISM(S): Oryza sativa (Rice) 
2015-04-27 | PXD000951 | Pride
29rnp Kinase M/z list inclusion method 
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