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TranscriptomicsAnalysis of ETS gene expression patterns uncovers novel ETS mediated gene silencing pathways in prostate cancers
Deregulated expression of ETS transcription factors with oncogenic and tumor suppressor function occurs frequently in prostate cancer leading to profound alterations of the cancer transcriptome. By integrating genomic and functional studies we identified key targets of the aberrantly expressed ETS ...
ORGANISM(S): Homo sapiens 
2010-06-09 | E-GEOD-14206 | biostudies-arrayexpress
TranscriptomicsATAC-seq to investigate rewiring the transcriptome of castration-resistant prostate cancer through CDK9 inhibition dataset 1
The rewiring of transcriptional and epigenetic programs is a hallmark of cancer and a targetable vulnerability for treating metastatic cancers. CDK9, whose primary function is to promote transcriptional elongation at active gene promoters, is emerging as a therapeutic target with broad efficacy in v...
ORGANISM(S): Homo sapiens 
2026-04-08 | E-MTAB-12986 | biostudies-arrayexpress
TranscriptomicsTranscription profiling and genotyping of 26 human mantle cell lymphoma samples
Among B-cell lymphomas mantle cell lymphoma (MCL) has the worst prognosis. By using a combination of genomic and expression profiling (Affymetrix GeneChip Mapping 10k Xba131 and U133 set), we analysed 26 MCL samples to identify genes relevant to MCL pathogenesis and that could represent new therapeu...
ORGANISM(S): Homo sapiens 
2007-06-24 | E-GEOD-4176 | biostudies-arrayexpress
UnknownThe Role of Registers in Increasing Knowledge and Improving Management of Children and Adolescents Affected by Familial Hypercholesterolemia: the LIPIGEN Pediatric Group.
Not available
S-EPMC9251337 | biostudies-literature
TranscriptomicsTranscription profiling of human monoclonal B-cell PTLD, collected from 20 solid organ transplant recipients
Post-transplant lymphoproliferative disorders (PTLD) are a major complication of solid organ transplantation and represent a cause of severe morbidity and mortality among transplanted patients. Apart from EBV infection, knowledge of the pathogenesis of monoclonal PTLD is limited. Powerful analysis t...
ORGANISM(S): Homo sapiens 
2008-06-16 | E-GEOD-8123 | biostudies-arrayexpress
TranscriptomicsThe network of genes regulated by Ago1 in metastatic prostate cancer PC3
The objective of this study was to evaluate the consequences of Ago1 knockdown in metastatic prostate cancer cells PC3. To this end we profiled RNA from PC3 cells 72 hours following the transfection with a scramble siRNA (siGL3) and a siRNA targeting Ago1 (siAgo1). We profiled RNA from PC3 cells 72 ...
ORGANISM(S): Homo sapiens 
2015-05-22 | E-GEOD-57885 | biostudies-arrayexpress
UnknownTime-Trends in Air Pollution Impact on Health in Italy, 1990-2019: An Analysis From the Global Burden of Disease Study 2019.
Not available
S-EPMC10280378 | biostudies-literature
TranscriptomicsHuman prostate carcinoma cell line 22Rv1 overexpressing ESE1
Activation of the inflammatory circuits occurs frequently in cancer cells. However the molecular details linking inflammation to transformation and progression are still unknown. In this study we report for the first time, that activation of the ETS factor ESE1 is a key event connecting inflammatory...
ORGANISM(S): Homo sapiens 
2013-06-20 | E-GEOD-39668 | biostudies-arrayexpress
UnknownClinical Approach in the Management of Paediatric Patients with Familial Hypercholesterolemia: A National Survey Conducted by the LIPIGEN Paediatric Group.
Not available
S-EPMC10420921 | biostudies-literature
UnknownDiagnosis and Screening Strategies for Detection of Familial Hypercholesterolaemia in Children and Adolescents in Italy: A Survey from the LIPIGEN Paediatric Group.
Not available
S-EPMC11941534 | biostudies-literature
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