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TranscriptomicsPolycomb CBX7 represses expression of tumor suppressor genes
Polycomb CBX7 was stably expressed in embryonal carcinoma cells in order to identify target genes. The study was specifically geared toward unveiling gene targets that are susceptible to DNA hypermethylation in adult cancer. A number of CBX7 target tumor suppressor genes were thereby identified an...
ORGANISM(S): Homo sapiens 
2009-09-23 | E-GEOD-10541 | biostudies-arrayexpress
TranscriptomicsGenes regulated by CBX7
We analyzed the expression profile of a thyroid carinoma cell line after the restoration of CBX7 expression.
ORGANISM(S): Homo sapiens 
2014-06-01 | E-MTAB-2420 | biostudies-arrayexpress
GenomicsChip-seq of Polycomb CBX7, H3K9me3 and H3K27me3 in huCD34+ CBX7 overexpressing cells
Chip-seq study for the genome-wide identification of CBX7 binding sites in CBX7 overexpressing CD34+ cellChip-seq study for genome-wide mapping of H3K9me3 and H3K27me3 in CD34+ cord blood cells upon overexpression of Polycomb CBX7 and Polycomb CBX8
PRJEB22344 | ENA
TranscriptomicsTranscriptome Analysis of Cbx7 Knockdown Effects in Ovarian Clear Cell Adenocarcinoma Cell Lines
Cbx7 knockdown resulted in increase of genes related with apoptosis and inflammation. Expression microarray was performed using RNA extracted from 2 ovarian clear cell adenocarcinoma cell lines, namely, KOC-7C and TOV21G, either trancduced by Cbx7 siRNA or control.
ORGANISM(S): Homo sapiens 
2013-11-01 | E-GEOD-47146 | biostudies-arrayexpress
GenomicsTranscriptome of CBX7 and CBX8 overexpressing CD34+ HSPCs
Transcriptome of CBX7 and CBX8 overexpressing CD34+ HSPCs
PRJEB22831 | ENA
GenomicsCBX7 Promotes Lung Adenocarcinoma Metastasis by Transcriptionally Repressing SOCS3
CBX7 Promotes Lung Adenocarcinoma Metastasis by Transcriptionally Repressing SOCS3
PRJNA1294140 | ENA
GenomicsPolycomb Cbx orthologs mediate the balance between Hematopoietic Stem Cell self-renewal and differentiation
By genome-wide ChIP-seq analyses we show that Cbx7 and Cbx8 share ~95% of their targets in bone marrow cells. Cbx7 and Cbx8 have only ~200 targets that are not overlapping between the two proteins. These distinct Cbx7 and Cbx8 targets show reciprocal expression patterns along hematopoietic different...
ORGANISM(S): Mus musculus 
2012-12-21 | E-GEOD-36658 | biostudies-arrayexpress
GenomicsConsequence of knock down of CBX7 in multiple cell lines
Consequence of knock down of CBX7 in multiple cell lines
PRJNA1068482 | ENA
GenomicsCBX7 is a tumour suppressor that inhibits bladder cancer
CBX7 is a tumour suppressor that inhibits bladder cancer
PRJNA664510 | ENA
TranscriptomicsPolycomb CBX7 represses expression of tumor suppressor genes
Polycomb CBX7 was stably expressed in embryonal carcinoma cells in order to identify target genes. The study was specifically geared toward unveiling gene targets that are susceptible to DNA hypermethylation in adult cancer. A number of CBX7 target tumor suppressor genes were thereby identified and ...
ORGANISM(S): Homo sapiens 
2009-09-23 | GSE10541 | GEO
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