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CCAR1 mRNA have two transcripts, the 3.5 kb full length transcript and the 2.5 kb shorter transcript which contained a deletion in exon 15—exon 22 of full-length CCAR1 cDNA, where sequences mapped to 1196–3120 bp were missed. CCAR1L and CCAR1S shared a common N-terminus and a common C-terminal end, ...
ORGANISM(S): Homo sapiens (Human) 
2018-05-15 | PXD009266 | Pride
The Splicing Factor CCAR1 Regulates the Fanconi Anemia/BRCA Pathway
The twenty-three Fanconi Anemia proteins cooperate in a DNA repair pathway, called the FA/BRCA pathway, required for the monoubiquitination of FANCD2 and the excision of interstrand DNA crosslinks (ICLs). The CCAR1 (cell division cycle and apoptosis regulator 1) protein is also a regulator of ICL re...
ORGANISM(S): Homo sapiens 
2024-08-21 | GSE242781 | GEO
Androgen receptor (AR) plays a critical role in prostate cancer onset and progression, and cell cycle and apoptosis regulator 1 (CCAR1) functions as an AR co-activator. We performed genome-wide gene expression analysis in control (shNS) and CCAR1-depleted (shCCAR1) LNCaP cells to assess the global e...
ORGANISM(S): Homo sapiens 
2013-10-01 | GSE45033 | GEO
Androgen receptor (AR) plays a critical role in prostate cancer onset and progression, and cell cycle and apoptosis regulator 1 (CCAR1) functions as an AR co-activator. We performed genome-wide gene expression analysis in control (shNS) and CCAR1-depleted (shCCAR1) LNCaP cells to assess the global e...
ORGANISM(S): Homo sapiens 
KDM4B-CCAR1-Mediator axis is a critical regulator of osteoclast differentiation and bone homeostasis
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