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MetabolomicsGlutaminolysis contribution to the carbon backbone of aspartate and glutamate in ccRCC
Not available
ORGANISM(S): Homo sapiens 
ST002222 | MetabolomicsWorkbench
ProteomicsThe mechanism of TRIM21 inhibiting the invasion and migration of ccRCC by stabilizing ASS1
Clear cell renal cell carcinoma (ccRCC) is characterized by its aggressive invasion and metastasis, posing significant clinical challenges. Understanding the molecular mechanisms underlying its progression is crucial for developing effective therapeutic strategies. The role of TRIM21 in regulating A...
ORGANISM(S): Homo Sapiens 
PXD054847 |
MetabolomicsGlutaminolysis contribution to the carbon backbone of aspartate through ATP Citrate Lyase (ACLY) in ccRCC
Not available
ORGANISM(S): Homo sapiens 
ST002221 | MetabolomicsWorkbench
ProteomicsCPTAC CCRCC Discovery Study - DIA Proteome
This is a supplementary study to the CPTAC CCRCC Discovery Study - Proteome. Unlabeled, digested peptide material from individual tissue samples (ccRCC and NAT) was spiked with index Retention Time (iRT) peptides (Biognosys) and subjected to data-independent acquisition (DIA) analysis. Kidney cance...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2023-10-04 | MSV000093041 | MassIVE
TranscriptomicsmicroRNAseq of clear-cell renal cell carcinoma on surgical resection specimens of untreated primary tumors in humans
We aimed to assess differences in miRNA expression profiles in transcriptomic molecular subtypes of ccRCC (Beuselinck et al, Clinical Cancer Research 2015) and to correlate miRNAs with overal survival since diagnosis of ccRCC. Sequencing was done for 129 primary ccRCC (formalin-fixed paraffin-embe...
ORGANISM(S): Homo sapiens 
2020-07-22 | E-MTAB-9380 | biostudies-arrayexpress
TranscriptomicsGlobal analysis of metastasis-associated gene expression in the primary cultures from clinical specimens of ccRCC
Metastatic clear cell renal cell carcinoma (ccRCC) has a poor prognosis and unpredictable course and there are no molecular markers that reliably predict ccRCC metastasis. In this study, specimens from 84 patients with ccRCC were directly cultured in vitro. The primary cultures from 38 of 94 specime...
ORGANISM(S): Homo sapiens 
2008-08-27 | E-GEOD-11072 | biostudies-arrayexpress
TranscriptomicsYAP conveys an invasive phenotype to clear cell renal cell carcinoma cell lines via endothelin-2
To determine the biological mechanisms underlying the oncogenic properties of YAP in ccRCC the human ccRCC cell line MZ1774 was transduced with lentivirus containing a shRNA-cassette targeting YAP-mRNA. Expression profiles of MZ1774 YAP knockdown cells were compared to mock-transduced control cells....
ORGANISM(S): Homo sapiens 
2014-12-23 | E-GEOD-50053 | biostudies-arrayexpress
ProteomicsLC-MS/MS proteomic profiling study of ccRCC cell-lines
We conducted comparative proteomic analysis with clear cell renal cell carcinoma (ccRCC), a subtype of RCC, have poorer prognosis and metastasize to the lungs, bones and lymph nodes. Comparative proteomic analysis in ccRCC study will reveals novel insights and development of disease.
ORGANISM(S): Homo sapiens (Human) 
2025-05-06 | PXD045898 | Pride
Ccrcc Silac Proteomic profiling 
MetabolomicsCoupled Mass-Spectrometry-Based Lipidomics Machine Learning Approach for Early Detection of Clear Cell Renal Cell Carcinoma

A discovery-based lipid profiling study of serum samples from a cohort that included patients with clear cell Renal Cell Carcinoma (ccRCC) stage I, II, III, and IV (n=112) and controls (n=52) was performed using ultraperformance liquid chromatography coupled to quadrupole-time-of-flight mass spec...

2020-11-20 | MTBLS1839 | MetaboLights
TranscriptomicsExpression data from pulmonary metastases and primary tumors of clear-cell renal cell carcinoma (ccRCC) with different disease-free survivals
The understanding of metastatic spread is limited and molecular mechanisms causing particular characteristics of metastasis are largely unknown. This comprises the extremely varying dormancy periods of tumor cells in the secondary organ after metastatic spread, represented by the disease-free surviv...
ORGANISM(S): Homo sapiens 
2010-07-30 | E-GEOD-22541 | biostudies-arrayexpress
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