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TranscriptomicsTranscription profile of CD103- vs CD103+ dendritic cells derived from CX3CR1+c-kit+- bone marrow cells (M1993 M2067)
We hypothesize that under homeostatic as well as inflammatory conditions circulating monocytes and/or their bone marrow-derived progenitors might contribute to the replenishment of CD103+ and CD103- DC in lymphoid and non-lymphoid compartments. To that end, bone marrow cells from CX3CR1+/gfp C57BL/6...
ORGANISM(S): Mus musculus 
2008-12-17 | E-GEOD-10882 | biostudies-arrayexpress
ProteomicsAn unconventional integrin b3 and CD103 heterodimer improves the anti-tumor immunity of tissue-resident T cells
Current cancer immunotherapies promote recovery of CD103+ tissue-resident memory T cells (Trm) population of the tumor-infiltrating T lymphocytes (TILs). However, not all treated patients exhibit improved anti-tumor immunity and survival, likely due to the immunophenotypical diversity among the C...
ORGANISM(S): Homo sapiens (Human) 
2024-02-14 | PXD031794 | Pride
Xcr1 Granulysin Itgb3 Tissue-resident Cancer immunotherapy Amino acids Cancer-specific t cells 
GenomicsWT and NLRP6 KO CD103+ and CD103- B cell expression
WT and NLRP6 KO CD103+ and CD103- B cell expression
PRJNA931300 | ENA
TranscriptomicsCross-presenting CD103+ dendritic cells are protected from influenza virus infection
CD8+ cytotoxic T cells are critical for viral clearance from the lungs upon influenza virus infection. The contribution of cross-presentation to the induction of anti-viral cytotoxic T cells remains debated. Here, we used a recombinant influenza virus expressing a NS1-GFP reporter gene to visualize ...
ORGANISM(S): Mus musculus 
2013-06-19 | E-GEOD-38838 | biostudies-arrayexpress
TranscriptomicsCD8+/CD103+ tumor-infiltrating lymphocytes are tumor-specific tissue-resident memory T cells and a prognostic factor for survival in lung cancer patients
We had previously demonstrated the role of CD103 integrin on lung tumor-infiltrating lymphocyte (TIL) clones in promoting specific TCR-mediated epithelial tumor cell cytotoxicity. However, the contribution of CD103 on intratumoral T-cell distribution and functions, and the prognosis significance of ...
ORGANISM(S): Homo sapiens 
2015-06-29 | E-MTAB-3266 | biostudies-arrayexpress
TranscriptomicsSheep skin lymph CD103 and CD11b -type DC in vitro response to Canine Adenovirus vector
Transcriptomic profiling of sheep skin lymph DC subsets after 16h in vitro culture in medium or stimulated by non replicative Canine Adenovirus serotype 2 Reference design: total enriched lymph dendritic cells- Biological replicates: 4 sheep (70958, 50274, 30066, 11261)- Samples: FACS sorted CD103 -...
ORGANISM(S): Ovis aries 
2012-11-30 | E-GEOD-42502 | biostudies-arrayexpress
TranscriptomicsGene expression profile in CD11c+ splenic dendritic cells and CD11c+CD103+ dendritic cells from mesenteric lymph nodes (MLN) of mice with DC-specific targeting of TGFBR2
Transcriptome analysis of dentritic cells from the spleen (CD11c+) or MLN (CD11c+CD103+) of mice with DC-specific deletion of TGFBR2 gene, or their control littermates. TRGFR2 gene was deleted in dendritic cells using Cre/lox approach. Mice with this deletion develop spontaneous multi-organ autoimmu...
ORGANISM(S): Mus musculus 
2012-07-25 | E-GEOD-39651 | biostudies-arrayexpress
TranscriptomicsIL-2Rβ- and CD103-dependent genes in regulatory T cells in the gut mucosa
This study determined the genes that are differentially expressed when regulatory T cells (Tregs) were isolated from the lamina propria of the small and large intestine from mice with impaired IL-2Rβ signaling (designated Y3) or impaired IL-2Rβ signaling and lack of CD103 expression (designated Y3/C...
ORGANISM(S): Mus musculus 
2015-01-06 | E-GEOD-56438 | biostudies-arrayexpress
TranscriptomicsThe transcriptional profile of human CD8+ lung resident memory T-cells
A specialized population of memory CD8+ T-cells resides in the epithelium of the respiratory tract to maintain protection against recurring infections. These cells express CD69 and the integrin αβ7 (CD103) and correspond to tissue resident memory T-cells (TRM) also described in intestine, liver an...
ORGANISM(S): Homo sapiens 
2016-10-23 | E-GEOD-61397 | biostudies-arrayexpress
TranscriptomicsExpression data from mouse colon dendritic cell subsets
Characterization of colon CD11chigh/MHCII+ myeloid cell subsets Colon lamina propria MHC+CD11chigh cells were sorted on the basis of CD103 and CD11b expression as follows: CD103+CD11b-, CD103+CD11b+, CD103-CD11b+.
ORGANISM(S): Mus musculus 
2015-08-24 | E-GEOD-58446 | biostudies-arrayexpress
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