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GenomicsClostridioides difficile CD109
Clostridioides difficile CD109 Genome sequencing and assembly
PRJNA85735 | ENA
ProteomicsCell surface processing of CD109 by meprin β leads to the release of soluble fragments and reduced expression on extracellular vesicles
Cluster of differentiation 109 (CD109) is a glycosylphosphatidylinositol (GPI) anchored protein expressed on primitive hematopoietic stem cells, activated platelets, CD4+ and CD8+ T-cells and keratinocytes. In recent years CD109 was also associated with different tumor entities and identified as a p...
ORGANISM(S): Mus musculus (Mouse) Homo sapiens (Human) 
2021-01-28 | PXD023727 | Pride
Cd109  macroglobulin  meprin β  exosomes  extracellular vesicles  tem  tep1r 
ProteomicsCD109 is novel KSHV entry receptor in human endothelial cells and enhances infection during cellular senescence
The aging process is characterized by cellular functional decline and increased susceptibility to infections. Understanding the association between virus infection and aging is crucial for developing effective strategies against viral infections in older individuals. Kaposi's sarcoma-associated herp...
ORGANISM(S): Homo sapiens (Human) 
2024-04-17 | PXD048212 | Pride
Kshv Cd109 Human endothelial cell Infection Cellular senescence 
GenomicsExpression data to parental A431 VS CD109 KO A431
Expression data to parental A431 VS CD109 KO A431
PRJNA482298 | ENA
GenomicsPatient-derived glioblastoma stem cells transcriptome regulation by CD109
Patient-derived glioblastoma stem cells transcriptome regulation by CD109
PRJNA716553 | ENA
GenomicsCD109 regulates in vivo tumor invasion in lung adenocarcinoma through TGF-β signaling
CD109 regulates in vivo tumor invasion in lung adenocarcinoma through TGF-β signaling
PRJNA649784 | ENA
TranscriptomicsSuppression of skin tumorigenesis in CD109-deficient mice
CD109 is a glycosylphosphatidylinositol-anchored glycoprotein that is highly expressed in several types of human cancers, particularly squamous cell carcinomas. We previously reported that CD109-deficient mice exhibit epidermal hyperplasia and chronic skin inflammation. Although we found that CD109 ...
ORGANISM(S): Mus musculus 
2016-09-28 | GSE87390 | GEO
UnknownCD109 plays a role in osteoclastogenesis.
Not available
S-EPMC3625217 | biostudies-literature
UnknownSuppression of skin tumorigenesis in CD109-deficient mice.
Not available
S-EPMC5347736 | biostudies-literature
TranscriptomicsPatient-derived glioblastoma stem cells transcriptome regulation by CD109
Glioma stem cells (GSCs) drive propagation and therapeutic resistance of glioblastomas, the most aggressive diffuse brain tumor. However, the molecular mechanisms that maintain the stemness and promote therapy resistance remain poorly understood. Here we study CD109 – STAT3 axis as crucial for the m...
ORGANISM(S): Homo sapiens 
2021-03-24 | GSE169418 | GEO
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