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TranscriptomicsNuclear Factor Kappa B is central to MarekM-bM-^@M-^Ys Disease lymphomagenesis
Chicken MarekM-bM-^@M-^Ys disease (MD) is a unique naturally occurring model for human herpesvirus-induced lymphomas that over-express the M-bM-^@M-^\HodgkinM-bM-^@M-^Ys disease antigenM-bM-^@M-^] (TNFRSF-8; CD30) on the lymphomaM-bM-^@M-^Ys neoplastically-transformed cells. We used transcriptomics,...
ORGANISM(S): Gallus gallus 
2012-03-15 | E-GEOD-28034 | biostudies-arrayexpress
TranscriptomicsDirect comparison of HES2 ESC overexpressing CD30 variant with HES2 overexpressing GFP
HES2 ESC were infected with a lentivirus construct containing either CD30 (TNFRSF8) extracellular deficient variant or GFP, using the ViraPower� Promoterless Lentiviral Gateway® Kits (Invitrogen). HES2 cells were recovered and grown for 19 passages. HES2 were commonly grown on Mouse Embryonic F...
ORGANISM(S): Homo sapiens 
2010-04-08 | E-GEOD-13261 | biostudies-arrayexpress
ProteomicsTargeting of CD30-negative tumor cells in DLBCL with Brentuximab-vedotin through CD30-positive extracellular vesicles, in vitro
Evaluate the composition of extracellular vesicles by mass spectrometry coupled with liquid chromatography.
ORGANISM(S): Homo sapiens (Human) 
2022-02-17 | PXD025442 | Pride
Tumor cells Extracellular vesicles Cd30 
TranscriptomicsGene expression in CD30+ L540 cell line induced by different anti-CD30 antibodies that bind to different epitopes
CD30 receptor (TNFRSF8) is highly expressed in some types of lymphoma. Therefore, CD30 is successfully used as a target for antibody-drug conjugate to treat CD30+ lymphoma. In this study, we compared gene expression profiles induced in CD30+ L540 cell line by treating CD30 natural ligand or anti-CD3...
ORGANISM(S): Homo sapiens 
2025-08-10 | GSE67794 | GEO
GenomicsGene Expression Profiling of Cutaneous CD30+ Lymphoproliferative Disorders by RNA-seq
Gene Expression Profiling of Cutaneous CD30+ Lymphoproliferative Disorders by RNA-seq
PRJNA431541 | ENA
TranscriptomicsGene Expression Profiling of Cutaneous CD30+ Lymphoproliferative Disorders by RNA-seq
Cutaneous CD30+ lymphoproliferative disorder (CD30+LPDs), including lymphomatoid papulosis (LyP) and primary cutaneous anaplastic large-cell lymphoma (PCALCL), comprises the second most common group of cutaneous T cell lymphoma. Previously, we reported that special AT-rich sequence-binding protein1 ...
ORGANISM(S): Homo sapiens 
2019-01-25 | GSE109620 | GEO
UnknownCD30-Positive Extracellular Vesicles Enable the Targeting of CD30-Negative DLBCL Cells by the CD30 Antibody-Drug Conjugate Brentuximab Vedotin.
Not available
S-EPMC8362802 | biostudies-literature
UnknownCD30-Redirected Chimeric Antigen Receptor T Cells Target CD30+ and CD30- Embryonal Carcinoma via Antigen-Dependent and Fas/FasL Interactions.
Not available
S-EPMC7590161 | biostudies-literature
TranscriptomicsComparison of gene expression between natural ligand treatment and agonistic antibody treatment in a CD30+ cell line
CD30 receptor (TNFRSF8) is highly expressed in some types of lymphoma. CD30 is successfully used as a target for antibody-drug conjugate to treat CD30+ lymphoma. The agonistic activity of the anti-CD30 antibody likely contributes to tumor cell killing. However, not all antibodies exhibit agonistic a...
ORGANISM(S): Homo sapiens 
2025-08-10 | GSE59174 | GEO
TranscriptomicsTranscription profiling of human non anaplastic T-cell lymphoma
A ﾑCartes dﾒIdentite des Tumeursﾒ (CIT) project from the french Ligue Nationale Contre le Cancer (http://cit.ligue-cancer.net) | Affymetrix HG-U133 Plus 2.0 : 17 AITL biopsies, 2 AITL sorted cells, 16 PTCL NOS biopsies | The molecular alterations underlying the pathogenesis of angioimmunoblast...
ORGANISM(S): Homo sapiens 
2009-09-22 | E-TABM-783 | biostudies-arrayexpress
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