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TranscriptomicsTranscription profiling of mouse CD45- and CD45+ cells in the embryonic lung
Side population (SP) cells are highly enriched in stem and progenitor cells. CD45+and CD45- SP cells were found at all developmental lung stages with the highest frequency of cells present at embryonic day 17.5 (E17.5), In order to clarify the role of these cells in lung development, we used oligonu...
ORGANISM(S): Mus musculus 
2007-11-23 | E-GEOD-2057 | biostudies-arrayexpress
ProteomicsCD45+ vs CD45- RCC proteome characterization
Exploration of proteome differences between CD45+ and CD45- cell types in renal cell carcinoma tumors and normal adjacent tissue patient samples.
ORGANISM(S): Homo sapiens (Human) 
2020-10-14 | PXD014370 | Pride
Renal cell carcinoma Cd45+ Normal adjacent tissue 
GenomicsClostridioides difficile CD45
Clostridioides difficile CD45 Genome sequencing and assembly
PRJNA85709 | ENA
TranscriptomicsTranscription profiling of mouse spleen from animals exposed to Ebola virus reveals reduced levels of protein tyrosine phosphatase CD45 protect mice from the lethal effects of Ebola virus infection
To gain insight into the changes in gene expression pattern upon Ebola infection, CD45+/+ (100% protein level) and CD45+/- (62% protein level) mice were challenged with mouse adapted Ebola virus. At time-points day 0, 1, 3, 5, 7, 9, 11 and 13, spleen tissue was harvested and splenocytes isolated. To...
ORGANISM(S): Mus musculus 
2009-09-05 | E-GEOD-17509 | biostudies-arrayexpress
TranscriptomicsGene expression profiles of CD4 T cells and CD45+ HLA-DR+ cells during experimental allergic rhinitis in humans.
Six patients with seasonal allergic rhinitis were challenged daily for 8 days with birch pollen extract. A mucosal biopsy was obtained from one nostril at basline (day 0) and from the other nostril after allergen challenge (day 9). The mucosal biopsies were digested into single cells, and then sorte...
ORGANISM(S): Homo sapiens 
2015-09-01 | E-GEOD-49782 | biostudies-arrayexpress
TranscriptomicsCombinatorial role of two paralogous splicing factors, hnRNP L and L-like, in multiple-exon regulation of CD45 alternative splicing
The goal of this study was to investigate the role of hnRNP L-like in alternative pre-mRNA splicing in human B-cells through an RNA-Seq approach. RNA-Seq was performed in DG75 cell line with over expression of hnRNP L-like or GFP as control.
ORGANISM(S): Homo sapiens 
2012-03-28 | E-GEOD-33013 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of mouse stromal cell compartment, lineage negative, CD45 negative bone marrow cells from C57B/L6 and B6.SJL (Ly5.1) strains
Comparison of gene expression in the stromal cell compartment (Lineage negative, CD45 negative bone marrow cells) of C57B/L6 and B6.SJL (Ly5.1) mice. duplicate samples were analyzed per strain (two biological replicates) and each of the two samples was pooled from 5 mice
ORGANISM(S): Mus musculus 
2010-01-20 | E-TABM-829 | biostudies-arrayexpress
TranscriptomicsFLT3 activation cooperates with MLL-AF4 fusion gene to abrogate the hematopoietic specification of human ESCs
MLL-AF4 is a hallmark genomic aberration which arises prenatally in high-risk infant acute lymphoblastic leukemia (ALL). In human embryonic stem cells (hESCs), MLL-AF4 skewed hemato-endothelial specification but was not sufficient for transformation. Additional cooperating genetic insults seem requi...
ORGANISM(S): Homo sapiens 
2013-06-04 | E-GEOD-40103 | biostudies-arrayexpress
GenomicsMaternal Schistosomiasis CD45+
Maternal Schistosomiasis CD45+
PRJNA680505 | ENA
GenomicsRhesus macaque cecal CD45+ leukocytes
Rhesus macaque cecal CD45+ leukocytes
PRJEB73798 | ENA
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