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TranscriptomicsGlobal gene expression analysis of CDCP1, KDM3B, and SDC1 knockdown in human marrow stromal cells
To elucidate functions of CDCP1, KDM3B and SDC1 molecules in HS5 human marrow stromal cells, global gene expression profiles were obtained and analyzed after knocking down the gene transcripts by using siRNA technology. Global gene expression profiles were obtained from HS5 marrow stromal cells afte...
ORGANISM(S): Homo sapiens 
2013-12-10 | E-GEOD-53199 | biostudies-arrayexpress
ProteomicsProteomic analysis of extracellular vesicles identifies CDCP1 as critical metastasis-related glycoprotein in lung cancer
Lung cancer is the most prevalent malignancy worldwide, with metastasis causing over 90% of fatalities. Recent studies have demonstrated the pivotal role of extracellular vesicles (EVs) and glycoproteins in tumor progression. In this study, we compared the glycoproteome of EVs from 95C (low metastat...
ORGANISM(S): Homo sapiens (Human) 
2025-08-04 | PXD057348 | Pride
Cdcp1 Extracellular vesicles Proteomics Lung cancer 
ProteomicsProteomic analysis of extracellular vesicles identifies CDCP1 as critical metastasis-related glycoprotein in lung cancer
Lung cancer is the most prevalent malignancy worldwide, with metastasis causing over 90% of fatalities. Recent studies have demonstrated the pivotal role of extracellular vesicles (EVs) and glycoproteins in tumor progression. In this study, we compared the glycoproteome of EVs from 95C (low metastat...
ORGANISM(S): Homo sapiens (Human) 
2025-08-04 | PXD064331 | Pride
Cdcp1 Extracellular vesicles Glycoproteomics Metastasis Lung cancer 
TranscriptomicsInteraction of CDCP1 with HER2 enhances HER2-driven tumorigenesis and promotes trastuzumab resistance in breast cancer
Our findings demonstrate that CDCP1 is a novel modulator of HER2 signalling, and a biomarker for the stratification of breast cancer patients with poor prognosis GEP analysis of human breast cancer cell lines SKBR3 overexpressing CDCP1 and control.
ORGANISM(S): Homo sapiens 
2016-01-08 | E-GEOD-67019 | biostudies-arrayexpress
GenomicsTranscriptomic profiling of CDCP1 knock-down in human cardiac fibroblasts (HCFs)
Transcriptomic profiling of CDCP1 knock-down in human cardiac fibroblasts (HCFs)
PRJNA923026 | ENA
ProteomicsDetection and isolation of circulating tumor cells from breast cancer patients using CUB domain-containing protein 1 (CDCP1) Detection and isolation of circulating tumor cells from breast cancer patients using CUB domain-containing protein 1 (CDCP1) Detection and isolation of circulating tumor cells from breast cancer patients using CUB domain-containing protein 1 (CDCP1)
Circulating tumor cells (CTCs) and disseminated tumour cells with mesenchymal traits are difficult to detect by epithelial marker proteins. Particularly, triple negative breast cancers (TNBC) that are prone to therapy failure release a subpopulation of circulating tumour cells (CTCs) with mesenchyma...
ORGANISM(S): Homo sapiens (Human) 
2023-03-20 | PXD035203 | Pride
Breast cancer Cdcp1 Bone marrow Circulating tumour cells Dissemination 
GenomicsRole of CDCP1 and Cardiac Fibrosis in a Mouse Model of Dilated Cardiomyopathy (DCM)
Role of CDCP1 and Cardiac Fibrosis in a Mouse Model of Dilated Cardiomyopathy (DCM)
PRJNA1295958 | ENA
TranscriptomicsTranscriptomic profiling of CDCP1 knock-down in human cardiac fibroblasts (HCFs)
To investigate the function of CDCP1 in regulation of HCF proliferation, we cultured primary HCFs and transfected with non-targeting siRNA and CDCP1 siRNAs. Total RNA samples were extracted for RNA-seq to identify transcriptome-wide gene expression changes in the HCFs after CDCP1 knock-down (KD).
ORGANISM(S): Homo sapiens 
2023-09-22 | GSE222695 | GEO
TranscriptomicsGene expression during CDCP1-induced morphological changes in MDCK cysts
Analysis of MDCK (type I) cysts overexpressing CDCP1-EGFP or its mutant. After cystogenesis in collagen matrix, overexpression of exogenous CDCP1 proteins was induced by the Tet-On system.
ORGANISM(S): Canis lupus familiaris 
2021-01-31 | GSE99375 | GEO
OtherRole of CDCP1 and Cardiac Fibrosis in a Mouse Model of Dilated Cardiomyopathy (DCM)
Cardiac fibrosis is a common pathological feature of various cardiac diseases that contributes significantly to heart failure progression and poor clinical outcomes. Recent genetic studies have shown that lower expression of CUB domain-containing protein 1 (CDCP1) is linked to myocardial recovery, b...
ORGANISM(S): Mus musculus 
2025-12-01 | GSE303631 | GEO
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