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ProteomicsA PTPB1-Cdk3 signaling axis promotes cell cycle progression of human glioblastoma cells through an Rb-E2F dependent pathway
Protein tyrosine phosphatase 1B (PTP1B) plays a key role in developing different types of cancer. However, the molecular mechanism underlying this effect is unclear. To identify possible molecular targets of PTP1B that mediate its positive role in tumorigenesis, we undertook a SILAC-based phosphopro...
ORGANISM(S): Homo sapiens (Human) 
2023-12-05 | PXD046000 | Pride
Ptpb1 Glioblastoma Cdk3 
UnknownCDK3, target of miR-4469, suppresses breast cancer metastasis via inhibiting Wnt/β-catenin pathway.
Not available
S-EPMC5689583 | biostudies-literature
UnknownCdk3, a conjugation-specific cyclin-dependent kinase, is essential for the initiation of meiosis in Tetrahymena thermophila.
Not available
S-EPMC5026800 | biostudies-literature
UnknownA PTP1B-Cdk3 Signaling Axis Promotes Cell Cycle Progression of Human Glioblastoma Cells through an Rb-E2F Dependent Pathway.
Not available
S-EPMC10761042 | biostudies-literature
TranscriptomicsmRNA sequencing of WT and cdk3∆ cells in conjugation 1, 2 and 3 (C1, C2 and C3) hours of Tetrahymena thermophila.
The goals of this study is to investigate the function of Cdk3 of Tetrahymena thermophila.
ORGANISM(S): Tetrahymena thermophila 
2017-08-15 | GSE80977 | GEO
UnknownPhosphorylation of NFAT3 by CDK3 induces cell transformation and promotes tumor growth in skin cancer.
Not available
S-EPMC5442426 | biostudies-literature
UnknownEZH2 regulates pancreatic cancer cells through E2F1, GLI1, CDK3, and Mcm4.
Not available
S-EPMC10190069 | biostudies-literature
UnknownEffect of microRNA-141-3p, E2F3, CDK3, and KAT2B overexpression on histologic tumor grade and metastasis status in untreated breast cancer tissues.
Not available
S-EPMC11830142 | biostudies-literature
UnknowncircRNA_141539 can serve as an oncogenic factor in esophageal squamous cell carcinoma by sponging miR-4469 and activating CDK3 gene.
Not available
S-EPMC8109109 | biostudies-literature
Proteomics,MultiomicsCyclin C-CDK3/8/19 kinases play a tumor-suppressive role in vivo
Cyclin C was cloned as a growth-promoting G1 cyclin1,2, and several studies postulated a role for cyclin C in driving cell proliferation3-8 . Moreover, cyclin C, together with its kinase partner, the cyclin-dependent kinase CDK8, is believed to represent an essential component of basal transcrip...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2017-03-29 | MSV000080728 | MassIVE
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