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MetabolomicsTraditional Aboriginal Preparation Alters the Chemical Profile of Carica papaya Leaves and Impacts on Cytotoxicity towards Human Squamous Cell Carcinoma
Carica papaya leaf decoction, an Australian Aboriginal remedy, has been used widely for its healing capabilities against cancer, with numerous anecdotal reports. In this study we investigated its in vitro cytotoxicity on human squamous cell carcinoma cells followed by metabolomic profiling of Carica...
2017-05-04 | MTBLS274 | MetaboLights
TranscriptomicsmiR expression during chondrogenic differenciation on mesenchymal stem cells
Differentiation of mesenchymal stem cells relies on precise control of tightly controlled genetic programme where specific sets of genes are up-regulated. Identification of miRNAs that are modulated during this process should help to better understand cho
ORGANISM(S): Homo sapiens 
2014-03-20 | E-MTAB-1544 | biostudies-arrayexpress
TranscriptomicsGenome wide analysis of gene expression in LPS stimulated splenic B cell.
Analysis of class switch recombination, maturation or differenciation of B cells at gene expression levels. The hypothesis tested in the present study was that TLR signaling in B cells plays an pivotal role for class switch, maturation and differenciation. Total RNA obtained from cultured splenic B ...
ORGANISM(S): Mus musculus 
2014-08-14 | E-GEOD-57837 | biostudies-arrayexpress
TranscriptomicsGenome wide analysis of gene expression in LPS stimulated splenic B cell.
Analysis of class switch recombination, maturation or differenciation of B cells at gene expression levels. The hypothesis tested in the present study was that TLR signaling in B cells plays an pivotal role for class switch, maturation and differenciation.
ORGANISM(S): Mus musculus 
2014-08-14 | GSE57837 | GEO
TranscriptomicsGlucocorticoid Resistance Gene Profiling in T-ALL Cell Lines
Baseline glucocorticoid resistance profiles were measured in a panel of 15 paediatric T-Cell acute lymphoblastic leukaemia cell lines and correlated with Affymetrix Gene expression to identify genes and pathways associated with drug resistance in T-ALL. The cell lines' resistance to Methylprednisolo...
ORGANISM(S): Homo sapiens 
2012-07-09 | E-MTAB-1208 | biostudies-arrayexpress
TranscriptomicsTranscriptomics of a novel trophoblast differentiation protocol applied to human embryonic stem cells
We report the transcriptomic dynamics and novel transcriptomic events discovered by using a novel protocol which differentiates human embryonic stem cells to the trophoblast lineage. We used five timepoints (day 0, 2, 4, 6, 8) to see the progression of differenciation. At each timepoint RNA was extr...
ORGANISM(S): Homo sapiens 
2014-05-01 | E-GEOD-26811 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of p68/72 deficient C2C12 cells cultured in either growth medium or differentiation medium to investigate the function of p68/p72 in muscle gene expression and skeletal C2C12 cell differentiation.
This project investigates the function of p68/p72 in muscle gene expression and skeletal C2C12 cell differentiation. p68/p72 in C2C12 cells cultured in either growth medium (GM) or differentiation medium (DM) was knocked down using shRNA p68/p72 retrovirus, and globle gene expression was profiled us...
ORGANISM(S): Mus musculus 
2007-11-29 | E-GEOD-5305 | biostudies-arrayexpress
TranscriptomicsTranscriptome analysis of Th9 CD4+ T cells differentiated with or without Il-1beta
We report that the Th9 differenciation program is boosted in presence of Il-1beta Examination of the expression profile of Th9 CD4+ T cells after 1 hour and 3 days of differentiation and after in vivo injection
ORGANISM(S): Mus musculus 
2014-05-23 | E-GEOD-54697 | biostudies-arrayexpress
UnknownImpact of Hanks Kinase-Dependent Phosphorylation of CodY on the Physiology and Virulence in Bacillus cereus.
Not available
S-EPMC12583987 | biostudies-literature
TranscriptomicsmiRNA-seq study between Th0 and Th17 cells
To explore the differences in miRNA profiles, naive CD4+CD62L+ helper T cells were sorted by magnetic cell sorting from spleens of female C57BL/6 mice and were induced to differentiate into Th1 or Th17 cells, then total RNA was extracted and miRNA-seq were conducted. The results showed that many mi...
ORGANISM(S): Mus musculus 
2016-07-30 | E-GEOD-80834 | biostudies-arrayexpress
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