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In aquatic environments, the production and consumption of organic compounds is directly tied to the metabolic potential of the in situ microbial community. The community’s metabolic potential can be assessed using metatranscriptomics, which is a measure of gene expression in the environment. More r...
2016-01-14 | MTBLS293 | MetaboLights
Various cancers such as colorectal cancer (CRC) are associated with alterations in protein glycosylation. CRC cell lines are frequently used to study these (glyco)biological changes and their mechanisms. However, differences between CRC cell lines with regard to their glycosylation have hitherto bee...
2017-02-03 | MTBLS227 | MetaboLights

BACKGROUND AND AIMS: Atherosclerosis, characterized by dysfunction of lipid metabolism and chronic inflammation, is considered as a metabolic disorder as well as a major contributor to cardiovascular diseases. However, metabolic signatures of atherosclerosis have not been well ex...

2024-09-26 | MTBLS9737 | MetaboLights
Xenobiotics are ubiquitous in the environment and modified abundantly in the human body by phase I and II metabolism. Liquid chromatography coupled to high resolution mass spectrometry is a powerful tool to investigate these biotransformation products. Here, we present a workflow based on stable iso...
2020-04-14 | MTBLS1358 | MetaboLights
Cell Surface Capture (Wollscheid et al., 2009, Nat.biotec.) was performed on various different cell types in order to characterize the cell surface proteome and to build the Cell Surface Protein Atlas.
ORGANISM(S): Mus musculus (Mouse) Homo sapiens (Human) 
2016-02-16 | PXD000589 | Pride
Cell surface proteins are responsible for many crucial physiological roles, and they are also the major category of drug targets as the majority of therapeutics target membrane proteins on the surface of cells to alter cellular signaling. How-ever, despite its great significance, ligand discovery ag...
ORGANISM(S): Homo Sapiens 
2024-03-01 | PXD042888 |
Large numbers of cells are generally required for quantitative global proteome profiling due to the significant surface adsorption losses associated with sample processing. Such bulk measurement obscures important cell-to-cell variability (cell heterogeneity) and makes proteomic profiling impossible...
ORGANISM(S): Homo Sapiens 
2021-03-11 | PXD022827 | panorama
The proteins on the surface of Y79 retinoblastoma cell line were analyzed by cell surface biotinylation and streptavidin affinity purification.
ORGANISM(S): Homo sapiens (Human) 
2024-01-26 | PXD039517 | Pride
The proteins on the surface of RB383 retinoblastoma cell line were analyzed by cell surface biotinylation and streptavidin affinity purification.
ORGANISM(S): Homo sapiens (Human) 
2024-01-26 | PXD039518 | Pride
In-situ glial cell-surface proteomics identifies pro-longevity factors in Drosophila
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