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MetabolomicsIn-depth organic mass cytometry reveals differential contents of 3-hydroxybutanoic acid at the single-cell level
Comprehensive single-cell metabolic profiling is critical for revealing phenotypic heterogeneity and elucidating the molecular mechanisms underlying biological processes. However, single-cell metabolomics remains challenging because of the limited metabolite coverage and inability to discriminate is...
2026-08-14 | MTBLS8113 | MetaboLights
MetabolomicsSingle cell lipidomics of adherent gut epithelial cell lines Caco2 and HT29-MTX reveals a metabolic switch

Raw MS data files for the CaCo02 and HT29-MTX single cells isolated using the Yokogawa SS2000 for the research article 'Single cell lipidomics of adherent gut epithelial cell lines Caco2 and HT29-MTX reveals a metabolic switch' 

2026-03-18 | MTBLS14074 | MetaboLights
TranscriptomicsGenome-wide survey of human alternative pre-mRNA splicing with exon junction microarrays
This series represents 52 tissues hybridized across 5 different chip patterns. Probes were placed at every exon-exon junction in each transcript. Keywords = junction alternate splicing oligonucleotide Keywords: parallel sample. This dataset is part of the TransQST collection.
ORGANISM(S): Homo sapiens 
2003-12-19 | E-GEOD-740 | biostudies-arrayexpress
ProteomicsDysregulation of Cell-Cell Interaction in Brain Arteriovenous Malformations: A Quantitative Proteomics Study
Object. Detailed and exact mechanisms underlying brain arteriovenous malformations (bAVM) are still confusing in clinic. Understanding the quantitative changes of proteins and signaling pathways would provide useful information for clinicians to understand the formation and development of bAVM and t...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2017-03-29 | MSV000080716 | MassIVE
TranscriptomicsThe exon junction complex regulates the splicing of cell polarity gene dlg1 to control Wingless signaling in development
Wingless (Wg)/Wnt signaling is conserved in all metazoan animals and plays critical roles in development. The Wg/Wnt morphogen reception is essential for signal activation, whose activity is mediated through the receptor complex and a scaffold protein Dishevelled (Dsh). We report here that the exon ...
ORGANISM(S): Drosophila melanogaster 
2016-08-19 | E-GEOD-81220 | biostudies-arrayexpress
TranscriptomicsLoss of tight junction integrity induces loss of epithelial phenotype: case of Claudin11 knock out in testis.
Epithelium barrier integrity is assumed at least in part by the presence of junctions between cells. Tight-junction formation may be necessary for Sertoli cells to cease dividing and to support germ cell development. Microarray analysis of P20 Cldn11 +/- and Cldn11-/- testes confirmed the impact od ...
ORGANISM(S): Mus musculus 
2010-04-11 | E-GEOD-15492 | biostudies-arrayexpress
TranscriptomicsExon and junction microarrays detect widespread mouse strain- and sex-bias expression differences
71 liver RNA samples from three mouse strains - DBA/2J, C57BL/6J and C3H/HeJ - were profiled using a custom-designed microarray monitoring exon and exon-junction expression of 1,020 genes representing 9,406 exons. Gene expression was calculated via two different methods, using the 3'-most exon prob...
ORGANISM(S): Mus musculus 
2010-05-25 | E-GEOD-10736 | biostudies-arrayexpress
ProteomicsMembrane prewetting by condensates promotes tight junction belt formation
Time-resolve proximity proteomics of tight junction. To understand how the tight junction belt is assembled and positioned, we combined APEX2 proximity proteomics of the main junctional scaffold protein ZO-1 with a calcium switch tissue formation assay.This combination allowed us to synchronize the ...
ORGANISM(S): Canis familiaris (Dog) (Canis lupus familiaris) 
2024-05-22 | PXD052221 | Pride
Canis lupus Tight junction Tmt Apex2 Mdck-ii 
TranscriptomicsTranscription profiling of mouse neuromuscular junction laser dissected at various time points vs. normal
NMJ Junction various time points normal C57BL10 LCM mRNA
ORGANISM(S): Mus musculus 
2008-06-12 | E-GEOD-2394 | biostudies-arrayexpress
ProteomicsIKKα modulates colorectal cancer metastasis by counteracting tight junction stabilization and collective cell migration.
The IKK kinase was previously found to activate multiple oncogenic and therapy-resistance pathways, including ATM/DDR, BRD4, and JAK/STAT3, independently of canonical NF-B signaling. Here, we show that suppression of IKK, either genetically or pharmacologically, imposes a pro-metastatic activity on ...
ORGANISM(S): Homo sapiens (Human) 
2025-12-01 | PXD057102 | Pride
Ikkα Cell migration. Colorectal cancer Metastasis 
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