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MetabolomicsSphingomyelin depletion inhibits CXCR4 dynamics and CXCL12-mediated directed cell migration in human T cells
Not available
ORGANISM(S): Homo sapiens 
ST002150 | MetabolomicsWorkbench
ProteomicsLocal RNA translation controls cell migration and Rab GTPase function
Numerous RNAs exhibit specific distribution patterns in mammalian cells. However, the functional and mechanistic consequences are relatively unknown. We investigate here the functional role of RNA localization at cellular protrusions of mesenchymal migrating cells, using as a model the RAB13 RNA, wh...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2020-08-01 | MSV000085883 | MassIVE
TranscriptomicsPARVB overexpression increases migration capability and defines high risks for endophytic growth and metastasis in tongue squamous cell carcinoma.
Tongue squamous cell carcinoma (TSCC) varies in characteristics even in early stages and is mainly classified into three subtypes, which are superficial, exophytic and endophytic types, based on a macroscopic appearance of tumor growth.Of these subtypes, endophytic tumor has a poorer prognosis becau...
ORGANISM(S): Homo sapiens 
2015-12-31 | E-GEOD-52915 | biostudies-arrayexpress
ProteomicsMigExpress discovers essential cell migration control genes in non-small cell lung cancer
Cell migration is an essential process in health and disease - especially in cancer metastasis. The difficulty to assess migration in high throughput presents a methodological hurdle - hence, only very few screens revealed factors controlling this important process. Here, we introduce MigExpress as...
ORGANISM(S): Homo sapiens (Human) 
2021-04-20 | PXD022146 | Pride
Proteomics Isobaric labeling Tandem mass tags (tmt) Non-small cell lung cancer (nsclc) Transcriptomics Cell migration 
GenomicsA Bidirectional Single-Cell Migration and Retrieval Chip for Quantitative Study of Dendritic Cell Migration
A Bidirectional Single-Cell Migration and Retrieval Chip for Quantitative Study of Dendritic Cell Migration
PRJNA856333 | ENA
TranscriptomicsNudt3 is a mRNA Decapping Enzyme That Modulates Cell Migration
The Dcp2 and Nudt16 Nudix hydrolases, are mRNA decapping enzymes that preferentially modulate stability of a subset of mRNAs. Here we report Nudt3 is a third Nudix protein that possess mRNA decapping activity in cells and is a modulator of cell migration in MCF-7 breast cancer cells. Genome-wide a...
ORGANISM(S): Homo sapiens 
2016-07-21 | E-GEOD-75146 | biostudies-arrayexpress
TranscriptomicsClaudin 1 mediates TNF alpha-induced gene expression and cell migration in human lung carcinoma cells
Epithelial-mesenchymal transition (EMT) is an important mechanism in carcinogenesis. To determine the mechanisms that are involved in the regulation of EMT is crucial to develop new biomarkers and therapeutic targets towards cancers. In this study, when TGFß1 and TNFa were used to induce EMT in hum...
ORGANISM(S): Homo sapiens 
2012-06-12 | E-GEOD-32254 | biostudies-arrayexpress
ModelsTumour Cell Invasion and Migration
Understanding the etiology of metastasis is very important in clinical perspective, since it is estimated that metastasis accounts for 90% of cancer patient mortality. Metastasis results from a sequence of multiple steps including invasion and migration. The early stages of metastasis are tightly co...
5884 | Cell Collective
ProteomicsBistability in the Rac1, PAK and RhoA signalling network is a feature of cell motility.
Dynamic interactions between RhoA and Rac1, members of the Rho small GTPase family, play a vital role in the control of cell migration. Using predictive mathematical modelling and experimental validation in MDA-MB-231 mesenchymal breast cancer cells, we show that Rac1 and RhoA interactions via the P...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2017-03-29 | MSV000080751 | MassIVE
TranscriptomicsStem Cell Antigen-1 (Sca-1) Regulates Mammary Tumor Development and Cell Migration
Stem cell antigen-1 (Sca-1 or Ly6A) is a member of the Ly6 family of glycosyl phostidylinositol (GPI)-anchored cell surface proteins. To determine the potential mechanisms by which Sca-1 regulates cell migration, adhesion, and tumor development; we performed an Affymetrix mouse genome 430A 2.0 array...
ORGANISM(S): Mus musculus 
2012-02-16 | E-GEOD-30684 | biostudies-arrayexpress
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