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In vertebrates, all cells except circulating blood cells must adhere to support their normal growth and functions. The adherence to extracellular matrix and/or other cells is critical and adherent cells placed in non-adherent conditions either die or form multicellular spheroids. Placing cells in no...
ORGANISM(S): Mus musculus (Mouse) 
2021-09-09 | PXD021593 | Pride
As adherence and entry of a pathogen into a host cell are two key components to an infection, identifying the molecular mechanisms responsible for cellular association will provide a better understanding of a microbe’s ability for pathogenesis. We previously established an in vitro model for B. b...
ORGANISM(S): Homo sapiens 
Bovine respiratory epithelial cells have different susceptibility to bovine respiratory syncytial virus infection. The cells derived from the lower respiratory tract were significantly more susceptible to the virus than those derived from the upper respiratory tract. Pre-infection with virus of lowe...
ORGANISM(S): Bos Taurus 
Knowledge on the dynamic features of the processes driven by malaria parasites in the spleen, our biggest lymphoid organ, is lacking. We have implemented intravital microscopy and magnetic resonance imaging of the mouse spleen in experimental infections with the Plasmodium yoelii non-lethal (17X) an...
ORGANISM(S): Mus musculus 
Global transcriptome analysis of B. burgdorferi during adherence and invasion of human neuroglial cells
As adherence and entry of a pathogen into a host cell are two key components to an infection, identifying the molecular mechanisms responsible for cellular association will provide a better understanding of a microbe’s ability for pathogenesis. We previously established an in vitro model for B. burg...
ORGANISM(S): Yersinia pestis Borreliella burgdorferi Chlamydia trachomatis Staphylococcus aureus Homo sapiens Coxiella burnetii Streptococcus pyogenes 
2008-06-20 | GSE8219 | GEO
Polystyrene microplastics induce activation and cell death of neutrophils through strong adherence and engulfment
The aim of this experiment was to characterize the gene expression of several in vitro cellular models of hepatocyte function: primary hepatocytes and common immortalized liver cell lines (HepG2, Hep3B and Huh7), cultured in parallel in both 2D and 3D configurations. Two independent cultures were c...
ORGANISM(S): Homo sapiens 
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