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ProteomicsCImP: Cellular Imprinting Proteomics applied to ocular disorders
A method (termed Cellular Imprinting Proteomics, CImP) for the identification and quantification of the ocular surface proteome using a minimally invasive membrane filter device is described. Moreover, The CImP method was applied to profile the molecular alterations in the eyes of infants exposed to...
ORGANISM(S): Homo sapiens (Human) 
2020-07-23 | PXD014038 | Pride
Cellular imprinting proteomic 
UnknownSnapshot imprinting as a tool for surface mapping and identification of novel biomarkers of senescent cells.
Not available
S-EPMC9724690 | biostudies-literature
ProteomicsHAP1 is an in vivo UBE3A Target that Augments Autophagy in a Mouse Model of Angelman Syndrome
Angelman syndrome (AS) is a severe neurodevelopmental disorder caused by maternal mutation and paternal imprinting of the gene encoding UBE3A, an E3 ubiquitin ligase. Although several potential target proteins of UBE3A have been reported, how these proteins regulate neuronal development remains uncl...
ORGANISM(S): Mus Musculus 
2018-12-15 | MSV000083239 | MassIVE
OtherPost-transcriptional Gene Silencing Mediated by microRNAs is Controlled by Nucleoplasmic Sfpq [HITS-CLIP]
There is a growing body of evidence about the presence and the activity of the miRISC in the nucleus of mammalian cells. Here, we show by quantitative proteomic analysis that Ago2 interacts with nucleoplasmic Sfpq in a RNA-dependent fashion. By HITS-CLIP and transcriptomic analyses, we demonstrated ...
ORGANISM(S): Mus musculus 
2017-10-20 | GSE89027 | GEO
TranscriptomicsPost-transcriptional Gene Silencing Mediated by microRNAs is Controlled by Nucleoplasmic Sfpq [Agilent]
There is a growing body of evidence about the presence and the activity of the miRISC in the nucleus of mammalian cells. Here, we show by quantitative proteomic analysis that Ago2 interacts with nucleoplasmic Sfpq in a RNA-dependent fashion. By HITS-CLIP and transcriptomic analyses, we demonstrated ...
ORGANISM(S): Mus musculus 
2017-10-20 | GSE89023 | GEO
TranscriptomicsPost-transcriptional Gene Silencing Mediated by microRNAs is Controlled by Nucleoplasmic Sfpq [RNA-Seq]
There is a growing body of evidence about the presence and the activity of the miRISC in the nucleus of mammalian cells. Here, we show by quantitative proteomic analysis that Ago2 interacts with nucleoplasmic Sfpq in a RNA-dependent fashion. By HITS-CLIP and transcriptomic analyses, we demonstrated ...
ORGANISM(S): Mus musculus 
2017-10-20 | GSE89032 | GEO
GenomicsPost-transcriptional Gene Silencing Mediated by microRNAs is Controlled by Nucleoplasmic Sfpq [RIP-Seq]
There is a growing body of evidence about the presence and the activity of the miRISC in the nucleus of mammalian cells. Here, we show by quantitative proteomic analysis that Ago2 interacts with nucleoplasmic Sfpq in a RNA-dependent fashion. By HITS-CLIP and transcriptomic analyses, we demonstrated ...
ORGANISM(S): Mus musculus 
2017-10-20 | GSE89031 | GEO
UnknownLong-term atorvastatin improves cognitive function by modulating SIRT2-mediated dynamic transition of NFL lysine 272 crotonylation to ubiquitination in naturally aging rats.
Not available
S-EPMC12533114 | biostudies-literature
GenomicsMus musculus
Post-transcriptional Gene Silencing Mediated by microRNAs is Controlled by Nucleoplasmic Sfpq [RNA-Seq]
PRJNA349978 | ENA
GenomicsMus musculus
Post-transcriptional Gene Silencing Mediated by microRNAs is Controlled by Nucleoplasmic Sfpq [RIP-Seq]
PRJNA349979 | ENA
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