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TranscriptomicsTranscriptional profiling of a wound healing process in skin and oral mucosa
When compared to skin, oral mucosal wounds heal rapidly and with reduced scar formation. This study used an Affymetrix microarray platform to compare the transcriptomes of oral mucosa and skin wounds in order to identify critical differences in the healing response at these two sites. Using microarr...
ORGANISM(S): Mus musculus 
2010-07-20 | E-GEOD-23006 | biostudies-arrayexpress
TranscriptomicsTranscription profiling by array of human patients with acute myeloid leukemia and chemotherapy-induced oral mucositis
Chemotherapy may cause DNA damage within the oral mucosa of cancer patients leading to mucositis, a dose-limiting side effect for effective cancer treatment. We used whole genome gene expression analysis to identify cellular damage to the mucosal tissue occuring two days post induction chemotherapy ...
ORGANISM(S): Homo sapiens 
2009-01-14 | E-GEOD-10746 | biostudies-arrayexpress
TranscriptomicsExpression data from oral squamous cell carcinoma (OSCC)-derived cell lines and normal oral keratinocytes
Oral squamous cell carcinoma (OSCC) is a lethal disease and early death usually occurs as a result of local invasion and regional lymph node metastases. We used microarrays to identify down or upregulated genes in OSCCs compared with non-malignant controls. To identify genes whose transcription is d...
ORGANISM(S): Homo sapiens 
2011-09-01 | E-GEOD-31853 | biostudies-arrayexpress
TranscriptomicsGenomic aberrations in distant fields from oral potentially malignant lesions by high resolution DNA flow cytometry and array-CGH
The aim of the study was to address the concept of field cancerization in oral cancer. The presence of genomic aberrations, indicative of chromosomal instability (CIN), in oral distant fields (ODFs) of visually normal and non-dysplastic mucosa at the mirror image from concomitant oral potentially ma...
ORGANISM(S): Homo sapiens 
2011-12-21 | E-GEOD-28906 | biostudies-arrayexpress
ProteomicsProteomic characterization of the mucosal pellicle formed in vitro on a cellular model of oral epithelium
The oral mucosal pellicle is a thin lubricating layer generated by the binding of saliva proteins on epithelial oral cells. The protein composition of this biological structure has been to date studied by targeted analyses of specific salivary proteins. In order to perform a more exhaustive proteome...
ORGANISM(S): Homo sapiens (Human) 
2020-05-06 | PXD017268 | Pride
Saliva Cellular model of oral mucosa Tr146/muc1 cells Mucosal pellicle 
TranscriptomicsOntogeny of Innate Immunity in Oral Mucosa - Cross Sectional
mRNA microarray profiling was performed on healthy gingival biopsies from nonhuman primates (NHPs) (between 3 and 23 years old, and periodontitis gingival biopsies from NHPs (12-22 years old)
ORGANISM(S): Macaca mulatta 
2014-10-15 | E-MTAB-1977 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human MSK-Leuk1 cells (a cellular model of oral leukoplakia) after tobacco smoke exposure to
In addition to being causally linked to the formation of multiple tumor types, tobacco use has been associated with decreased anticancer treatment efficacy and reduced survival time. A detailed understanding of the cellular mechanisms that are affected by tobacco smoke should facilitate the developm...
ORGANISM(S): Homo sapiens 
2008-10-21 | E-GEOD-10063 | biostudies-arrayexpress
UnknownHepcidin expression in the trigeminal ganglion and the oral mucosa in an oral ulcerative mucositis rat model.
Not available
S-EPMC10118189 | biostudies-literature
UnknownCharacterization of an ester-based core-multishell (CMS) nanocarrier for the topical application at the oral mucosa.
Not available
S-EPMC8443517 | biostudies-literature
GenomicsOral mucosal host-microbiome model
Development of an oral mucosa model to study host-microbiome interactions during wound healing
PRJEB5215 | ENA
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