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The interplay of cellular determinants shapes human and avian influenza A virus tropism in the airway epithelium
Intestinal tuft cells are the physiologic target cell of murine norovirus and this tropism determines transkingdom interactions.
The present pandemic by Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) is driving increased research activities in order to understand the basic biology of the virus and determining effective therapeutic strategies. The commonly used laboratory cell-lines of human origin are the first ...
ORGANISM(S): Homo sapiens (Human) 
2021-04-14 | PXD023760 | Pride
Transcriptomic profiling of thymic dysregulation and viral tropism after neonatal roseolovirus infection
The host response of the primary intestinal epithelium to human astrovirus (HAstV infection has not been elucidated to date. In order to characterize the global effects of AstV infection on human intestinal tissue, we performed transcriptional profiling of VA1-infected human intestinal enteroids (HI...
ORGANISM(S): Homo sapiens 
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