Cerebral organoid

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Lab of Neuroproteomics, Department of Biochemistry and Tissue Biology, Institute of Biology, University of Campinas (UNICAMP), Campinas, SP, Brazil (2)
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Biomedical Research Institute, Foundation for Research and Technology-Hellas, University Campus, 45110 Ioannina, Greece (1)
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Proteomics Unit, Institute of Chemistry, Federal University of Rio de Janeiro (UFRJ), Rio deJaneiro, Brazil. Precision Medicine Research Center, Institute of Biophysics Carlos Chagas Filho, Federal University of Rio de Janeiro (UFRJ), Rio de Janeiro, Brazil. (1)
RECAMO, Masaryk Memorial Cancer Institute Zluty Kopec, Brno, Czech Republic (1)
Strand Leader BENM, Lloyd Sansom Chair Future Industries Institute, UniSA (1)
University Health Network, University of Toronto (1)

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Lineage recording in human cerebral organoids (microdissected)

Induced pluripotent stem cell (iPSC) derived organoid systems provide models to study human organ development. Single-cell transcriptome sequencing enables highly-resolved descriptions of cell state heterogeneity within these systems and computational methods can reconstruct developmental trajectori...

ORGANISM(S): Homo sapiens

2021-11-03 | E-MTAB-10973 | biostudies-arrayexpress

Lineage recording in human cerebral organoids (Visium)

ORGANISM(S): Homo sapiens

2021-11-03 | E-MTAB-10972 | biostudies-arrayexpress

Lineage recording in human cerebral organoids (whole organoids)

ORGANISM(S): Homo sapiens

2021-11-03 | E-MTAB-10974 | biostudies-arrayexpress

Lineage recording in human cerebral organoids (iTracer-perturb)

ORGANISM(S): Homo sapiens

2021-11-03 | E-MTAB-10971 | biostudies-arrayexpress

Human cerebral organoid proteome

We investigated temporal proteomic changes of human cerebral organoids during neuroanl differentiations. TMT-based quantitative proteomics analysis of cerebral organoids at multiple time potins (day 0, 25, 43, 70 and 120) was performed using two-dimensional nanoflow liquied chromatography-tandem mas...

ORGANISM(S): Homo sapiens (Human)

2024-03-15 | PXD041173 | Pride

Multiome experiment of the neuroepithelial stage of brain organoid developement

To investigate the heterogeneity during the neuroepithelial stage of organoid development, we performed a multiome experiment on day 15-18 old brain organoids

ORGANISM(S): Homo sapiens

2022-10-03 | E-MTAB-12004 | biostudies-arrayexpress

Single-cell ATAC-seq of human cerebral organoids

Single cell ATAC-seq (scATAC-seq) was performed at various stages of differentiation of human pluripotent stem cells to 4 month old cerebral organoids. scATAC-seq was performed on the following days of differentiation: day 0 (pluripotent stem cell), day 4 (embryoid body), day 10 (neuroectoderm), day...

ORGANISM(S): Homo sapiens

2019-10-16 | E-MTAB-8089 | biostudies-arrayexpress

Proteomic analysis of Cerebral organoid-derived exsome

In this study, we provides a comprehensive analysis of proteomic changes in exosomes derived from cerebral organoids during neuronal differentiation.

ORGANISM(S): Homo sapiens (Human)

2026-04-27 | PXD063105 | Pride

Exosome Cerebral organoids Proteome

Single-cell transcriptome of cerebral organoids with and without methanol fixation

To study how methanol fixation affects single-cell transcriptomic measurement, two cerebral organoids were dissociated. Cell suspension of each organoid was split into two aliquots. Methanol fixation was applied to one of the two aliquots. Single-cell RNA-seq with 10x Genomics was applied to the two...

ORGANISM(S): Homo sapiens

2020-08-31 | E-MTAB-9473 | biostudies-arrayexpress

Single-cell ATAC-seq of bonobo cerebral organoids

Single cell ATAC-seq (scATAC-seq) was performed on bonobo induced pluripotent stem cells (iPSC) derived cerebral organoids. scATAC-seq was performed on day 60 (2 months old cerebral organoid) and day 120 (4 months old cerebral organoid).

ORGANISM(S): Pan paniscus

2019-10-16 | E-MTAB-8083 | biostudies-arrayexpress

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