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Cerebrovasculature in brain malignancies from 13 surgical resected samples
Cerebrovascular dysfunction is a hallmark feature of Alzheimer's disease (AD). One of the greatest risk factor for AD is the apolipoprotein E4 (E4) allele. APOE4 genotype has been shown to negatively impact on perivascular amyloid clearance, however, its direct influence along with the other APOE va...
ORGANISM(S): Homo sapiens (Human) 
2021-03-23 | PXD023340 | Pride
Dysfunction in human cerebrovasculature contribute to pathogenesis of multiple neurological diseases, and the blood brain barrier (BBB), an organotypic specialization of the cerebrovasculature, impedes the delivery of systemic therapies for nearly all brain disorders.Here we developed a novel method...
ORGANISM(S): Homo sapiens 
2024-08-26 | GSE242044 | GEO
Blockade of VCAM1 or VLA4 preserves cerebrovasculature and prevents cognitive decline late after stroke
Endothelial Pd1 orchestrates cerebrovasculature homeostasis and oligodendrogenesis during brain development
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