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ProteomicsProteomic characterization of extracellular matrix (ECM) produced by human fibroblast activation protein (FAP)-positive pericyte-like cells and glioma cells
Fibroblast activation protein (FAP) is upregulated in most cancers and represents an emerging theranostic target in oncology. In glioblastoma (GBM), FAP is predominantly expressed in mesenchymal pericyte-like cells, which contribute to GBM progression by promoting angiogenesis and glioma cell prolif...
ORGANISM(S): Homo Sapiens 
2024-05-07 | PXD045057 | panorama
ProteomicsA porcine spectral assay library to quantify brain proteome by DIA-MS
The peptide-centric analysis requires spectral assay libraries that allow for the extraction of quantitative data in mass spectrometry-based methods, including data-independent acquisition (DIA), parallel reaction monitoring (PRM), or selected reaction monitoring (SRM). Such spectral libraries have ...
ORGANISM(S): Sus scrofa domesticus (domestic pig) 
2026-05-18 | PXD074603 | Pride
ProteomicsWhole-proteome profiling of human lung cancer brain metastasis-associated fibroblasts
Cancer-associated fibroblasts (CAFs) are increasingly recognized as an important component of the brain metastasis tumour microenvironment; however, their proteomic phenotype remains poorly characterized. This dataset contains mass spectrometry-based proteomic profiles of primary human brain metasta...
ORGANISM(S): Homo sapiens (Human) 
2026-08-03 | PXD080067 | Pride
Primary cell culture Cell migration Lc-ms Brain metastases Cancer-associated fibroblasts Extracellular matrix 
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