Sort   by:  
 Page size 
ProteomicsHuman thyroid cell line complex CF-DIA-MS
This project aims to explore the protein interaction network of thyroid cancer cell lines through a robotics platform combined with proteomic techniques. The primary method involves using CF-DIA-MS (Co-fractionation Data-Independent Acquisition Mass Spectrometry) to acquire data from three different...
ORGANISM(S): Homo sapiens (Human) 
2025-12-20 | PXD059608 | Pride
Human Thyroid Cell line Cf-dia-ms 
ProteomicsProfiling protein-protein interactions in human brain by refined co-fractionation mass spectrometry
Proteins are essential regulators of biological processes and can have diverse functions depending on their interactions with other proteins. To understand deeply the interaction and their complexes, co-fractionation mass spectrometry (CF-MS) was used with ion exchange chromatography columns and dat...
ORGANISM(S): Homo sapiens (Human) 
2024-03-21 | PXD044084 | Pride
Protein-protein interaction Co-fractionation mass spectrometry Data-independent acquisition 
ProteomicsProfiling protein-protein interactions in human brain by refined co-fractionation mass spectrometry
Proteins are essential regulators of biological processes and can have diverse functions depending on their interactions with other proteins. To understand deeply the interaction and their complexes, co-fractionation mass spectrometry (CF-MS) was used with ion exchange chromatography columns and dat...
ORGANISM(S): Homo sapiens (Human) 
2024-03-21 | PXD044083 | Pride
Protein-protein interaction Co-fractionation mass spectrometry Data-independent acquisition 
Proteomicsmini-Complexome Profiling, an FDR-controlled workflow for global targeted Detection of protein complexes (Heart Data)
Co-fractionation mass spectrometry experiments (CF-MS) using native-like protein separations such as Blue Native electrophoresis (BNE) or size exclusion chromatography (SEC) enable a global characterization of protein networks, and a better understanding of cellular functions. They do, however, pose...
ORGANISM(S): Mus musculus (Mouse) 
2024-07-25 | PXD049426 | Pride
Protein complexes Proteomics Blue native electrophoresis Protein-protein interactions Data-independent acquisition Systems biology 
ProteomicsTFEB regulates protein synthesis to sustain autophagy during starvation
In response to starvation, cells undergo a metabolic shift to ensure their survival by shutting down protein synthesis and activating catabolic processes, including autophagy, to degrade proteins and recycle nutrients. These processes, however, do require protein synthesis. We asked how this fundame...
ORGANISM(S): Homo sapiens (Human) 
2020-09-30 | PXD016149 | Pride
Human hek293 
Proteomicsmini-Complexome Profiling, an FDR-controlled workflow for global targeted Detection of protein complexes (Hek293 data)
Co-fractionation mass spectrometry experiments (CF-MS) using native-like protein separations such as Blue Native electrophoresis (BNE) or size exclusion chromatography (SEC) enable a global characterization of protein networks, and a better understanding of cellular functions. They do, however, pose...
ORGANISM(S): Homo sapiens (Human) 
2024-07-25 | PXD049340 | Pride
Protein complexes Proteomics Blue native electrophoresis Protein-protein interactions Data-independent acquisition Systems biology 
ProteomicsCharacterization of the intratumoral heterogeneity using single cell-derived spheroids shows the involvement of metabolic changes during the metastatic cascade of colorectal cancer
Background: Colorectal cancer (CRC) stands as a significant contributor to cancer-related mortality globally. Approximately 90% of cancer mortality is due to distant metastasis. In the context of therapy, response rates can fluctuate significantly with approximately one-third of the patients experie...
ORGANISM(S): Homo sapiens (Human) 
2026-02-02 | PXD053393 | Pride
Intratumoral heterogeneity  single cells  spheroids  proteomics  aggresssiveness  metastatis  therapy resistance  intertumoral heterogeneity 
ProteomicsSecretomes from non-small cell lung cancer cells induce endothelial plasticity through a partial endothelial-to-mesenchymal transition
The tumor microenvironment (TME) of non-small cell lung cancer (NSCLC) is highly heterogeneous and is involved in tumorigenesis and resistance to therapy. Among the cells of the TME, endothelial cells are associated with the latter processes through endothelial-to-mesenchymal transition (EndMT). Dur...
ORGANISM(S): Homo sapiens (Human) 
2025-04-24 | PXD054295 | Pride
Human Emt Dia-pasef Non-small cell Lung cancer Secretome 
ProteomicsTranscriptome and proteome profiling of activated cardiac fibroblasts supports target prioritization in cardiac fibrosis
Activated cardiac fibroblasts (CF) play a central role in cardiac fibrosis, a condition associated with most cardiovascular diseases. Conversion of quiescent into activated CF sustains heart integrity upon injury. However, permanence of CF in active state inflicts deleterious heart function effects....
ORGANISM(S): Homo sapiens (Human) 
2023-03-10 | PXD034244 | Pride
Cardiac fibroblasts  cardiac fibrosis  myofibroblasts  transcriptomics  quantitative proteomics 
UnknownSARS-CoV-2 infection and venous thromboembolism after surgery: an international prospective cohort study.
Not available
S-EPMC8652887 | biostudies-literature
Sort   by:  
 Page size