Cftr modulator - OmicsDI

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Identification of early changes in multiple biomarkers following CFTR modulator initiation in patients with cystic fibrosis.

Not available

S-EPMC12515279 | biostudies-literature

Transcriptomic and functional responses of the cystic fibrosis airway epithelium to CFTR modulator therapy

PRJNA1311026 | ENA

CFTR modulator therapy enhances peripheral blood monocyte contributions to immune responses in people with cystic fibrosis

PRJNA623007 | ENA

Anti-inflammatory and phosphorylation effects of CFTR modulator triple therapy in cystic fibrosis

PRJNA1225598 | ENA

The CFTR Amplifier Nesolicaftor Rescues TGF-β1 Inhibition of Modulator-Corrected F508del CFTR Function.

Not available

S-EPMC9504033 | biostudies-literature

Heterogeneity of CFTR modulator-induced sweat chloride concentrations in people with cystic fibrosis.

Not available

S-EPMC11322419 | biostudies-literature

CFTR Modulator Response in Nasal Organoids Derived from People with Cystic Fibrosis.

Not available

S-EPMC12691081 | biostudies-literature

Changes in fecal microbiota with CFTR modulator therapy: A pilot study.

Not available

S-EPMC8243394 | biostudies-literature

Validation of nasospheroids to assay CFTR functionality and modulator responses in cystic fibrosis.

Not available

S-EPMC8324871 | biostudies-literature

Systemic effects of cystic fibrosis transmembrane conductance regulator (CFTR) modulators on the plasma and serum proteome

Cystic fibrosis (CF), resulting from a dysfunction in the cystic fibrosis transmembrane conductance regulator (CFTR), affects multiple organs through mucus obstruction and differences in secretion. The CFTR modulator drug combination elexacaftor/tezacaftor/ivacaftor (ELX/TEZ/IVA, ETI) has markedly i...

ORGANISM(S): Homo sapiens (Human)

2026-04-14 | PXD071549 | Pride

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