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We evaluate the quantitative performance of the newly released Asymmetric Track Lossless (Astral) analyzer. Using data independent acquisition, the Orbitrap Astral mass spectrometer quantifies 5 times more peptides per unit time than state-of-the-art Orbitrap mass spectrometers, which have long been...
ORGANISM(S): Homo Sapiens 
2023-09-18 | PXD042704 | panorama
This dataset contains an evaluation of TMT-based multiplexed proteomics on the Orbitrap Astral mass spectrometer.
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2024-12-17 | MSV000096674 | MassIVE
The study describes the use of PTMScan enrichment and LC-MS/MS analysis using Orbitrap Astral for the deep coverage of different PTM peptides from cells and tissue.
ORGANISM(S): Mus musculus (Mouse) Homo sapiens (Human) 
2026-05-21 | PXD065579 | Pride
We highlight the leap in performance made possible with new instrumentation in the Thermo Scientific Orbitrap Astral™ mass spectrometer. Integrated alongside a high-resolution accurate mass (HRAM) Orbitrap analyzer, the instrument introduces a fast-switching quadrupole mass filter congruent with dow...
ORGANISM(S): Homo sapiens (Human) 
2024-03-29 | PXD049028 | Pride
High-throughput proteomics is critical for understanding biological processes, enabling large-scale studies such as biomarker discovery and systems biology. However, current mass spectrometry technologies face limitations in speed, sensitivity, and scalability for analyzing large sample cohorts. The...
ORGANISM(S): Homo sapiens (Human) Escherichia coli Saccharomyces cerevisiae (Baker's yeast) 
2026-01-26 | PXD071972 | Pride
Canonical Hedgehog Signaling Controls Astral Microtubules and Mitotic Spindle Orientation in Neural Progenitors and iPSCs
High-throughput proteomics is critical for understanding biological processes, enabling large-scale studies such as biomarker discovery and systems biology. However, current mass spectrometry technologies face limitations in speed, sensitivity, and scalability for analyzing large sample cohorts. The...
ORGANISM(S): Homo sapiens (Human) 
2026-02-16 | PXD066927 | Pride
DIA analysis of sheep EVs using Evosep one and Orbitrap Astral
ORGANISM(S): Ovis aries 
2026-09-14 | PXD077206 | Pride
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