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ProteomicsComparative whole cell proteomics data of Vibrio cholerae O1 biovar El Tor str. N16961 versus full length cgtA knockdown and CgtA(∆CTD) during nutrient limiting condition
Adapting to nutritional downshifts is crucial for the survival of Vibrio cholerae. CgtA, a 50S ribosome-associated essential GTPase, is a bonafide stringent response protein. CgtA, in association with SpoT, modulates the intracellular (p)ppGpp alarmone levels in a nutrient-rich environment. We studi...
ORGANISM(S): Vibrio cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba N16961) Bacteria 
2023-03-03 | PXD034015 | Pride
Cgta gtpase C-terminal domain cgta truncation Nutrient limitation Vibrio cholerae Ribosome Pleiotropic effects Cgta knockdown 
GenomicsComparative RNA Seq studies of Vibrio cholerae O1 biovar El Tor str. N16961 versus full length cgtA knockdown during nutrient limiting condition
Insights into the pleiotropic responses as a resultant of cumulative stresses in Vibrio cholerae emerging from nutrient limitation coupled with depletion of an essential 50S ribosome associate GTPase CgtA
PRJEB53015 | ENA
UnknownThe Escherichia coli GTPase CgtAE is involved in late steps of large ribosome assembly.
Not available
S-EPMC1595513 | biostudies-literature
UnknownKnockdown Experiment Reveals an Essential GTPase CgtA's Involvement in Growth, Viability, Motility, Morphology, and Persister Phenotypes in Vibrio cholerae.
Not available
S-EPMC10100748 | biostudies-literature
UnknownThe Vibrio harveyi GTPase CgtAV is essential and is associated with the 50S ribosomal subunit.
Not available
S-EPMC1347350 | biostudies-literature
TranscriptomicsExpression data from Escherichia coli strains with increased or decreased levels of Obg (ObgE, CgtA, YhbZ)
We measured transcriptional changes resulting from overexpression or downregulation of the GTPase Obg.
ORGANISM(S): Escherichia coli 
2015-06-01 | GSE62918 | GEO
UnknownThe Neisseria gonorrhoeae Obg protein is an essential ribosome-associated GTPase and a potential drug target.
Not available
S-EPMC4487204 | biostudies-literature
GenomicsEscherichia coli
Expression data from Escherichia coli strains with increased or decreased levels of Obg (ObgE, CgtA, YhbZ)
PRJNA266102 | ENA
UnknownComprehensive in silico analyses of fifty-one uncharacterized proteins from Vibrio cholerae.
Not available
S-EPMC11452002 | biostudies-literature
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