Chai Chen C - OmicsDI

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Unknown (693)
Proteomics (16)
Transcriptomics (2)
Metabolomics (2)

Organisms

Homo sapiens (12)
Vitis vinifera (1)
Staphylococcus aureus (1)
Staphylococcus aureus subsp. aureus NCTC 8325 (1)
Alligator sinensis (1)
Mus musculus (1)
Sus scrofa domesticus (1)

Repository

pride (12)
iProX (4)
biostudies-arrayexpress (2)
MetaboLights (2)

Tissue

Cell culture (3)
Liver (2)
Blood cell (1)
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Cell suspension culture (1)
Epithelial cell (1)
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Malignant cell (1)
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Neutrophil (1)

Disease

Breast cancer (1)
Disease free (1)
Liver cancer (1)
Pancreatic carcinoma (1)
Pancreatic ductal adenocarcinoma (1)
Severe acute respiratory syndrome (1)

Technology Type

Mass Spectrometry (12)
Bottom-up proteomics (3)
Data-dependent acquisition (3)
Shotgun proteomics (3)
Mass spectrometry (2)
Data-independent acquisition (1)
DiaPASEF (1)
Gel-based experiment (1)
Mass spectrometry imaging (1)
SWATH MS (1)

Instrument Platform

Liquid Chromatography MS - negative - reverse phase (2)
Liquid Chromatography MS - positive - reverse phase (2)
Illumina HiSeq 2000 (1)

Publication Date

2025 (8)
2021 (4)
2023 (2)
2014 (1)
2008 (1)
2020 (1)
2022 (1)
2026 (1)
2018 (1)

CHEBI ID

CHEBI:10043 (1)
CHEBI:10072 (1)
CHEBI:10138 (1)
CHEBI:1015 (1)
CHEBI:102130 (1)
CHEBI:102265 (1)
CHEBI:102484 (1)
CHEBI:10275 (1)
CHEBI:10319 (1)
CHEBI:10353 (1)
CHEBI:104011 (1)
CHEBI:111762 (1)
CHEBI:113 (1)
CHEBI:116931 (1)
CHEBI:125610 (1)
CHEBI:125678 (1)
CHEBI:132244 (1)
CHEBI:132506 (1)
CHEBI:132966 (1)
CHEBI:132983 (1)
CHEBI:133094 (1)
CHEBI:134622 (1)
CHEBI:135071 (1)
CHEBI:135451 (1)
CHEBI:135590 (1)
CHEBI:135849 (1)
CHEBI:136805 (1)
CHEBI:137347 (1)
CHEBI:138308 (1)
CHEBI:138746 (1)

Metabolite Name

(+/-)-c75 (1)
(+/-)12(13)-DiHOME (1)
(-)-camphor (1)
(-)-caryophyllene oxide (1)
(9cis)-retinal (1)
-alanine (1)
-aspartylphenylalanine (1)
1-aminocyclohexanecarboxylic acid (1)
1-ethoxynaphthalene (1)
1-linoleoyl glycerol (1)
1-methyl-L-histidine (1)
1-methyladenosine (1)
1-methylguanine (1)
1-methylnicotinamide (1)
1-methyluric acid (1)
1-naphthol (1)
1-oleoyl-rac-glycerol (1)
1-phenylethanol (1)
10-HDA (1)
11-hydroxy-17-methyltestosterone (1)
12-aminododecanoic acid (1)
17-ethynylestradiol (1)
17-hydroxyprogesterone (1)
18-beta-glycyrrhetinic acid (1)
19-nortestosterone (1)
2'-O-methylguanosine (1)
2-(1-adamantylcarbonyl)hydrazine-1-carbothioamide (1)
2-(propylthio)nicotinic acid (1)
2-amino-3-methoxybenzoic acid (1)
2-amino-4-cresol (1)

Study type

Genotyping by array (1)
RNA-seq of coding RNA (1)

Release Date

2022 (111)
2025 (105)
2024 (94)
2023 (77)
2021 (75)
2020 (50)
2019 (41)
2018 (33)
2026 (19)
2014 (18)
2015 (17)
2017 (15)
2016 (12)
2012 (11)
2013 (7)
2011 (4)
2008 (2)
2009 (2)
2007 (1)
2006 (1)

Lab affiliation

1 Department of Hepatobiliary & Pancreatic Surgery, Zhongnan Hospital of Wuhan University, Wuhan, 430071, PR China. 2 Clinical Medicine Research Center for Minimally Invasive Procedure of Hepatobiliary & Pancreatic Diseases of Hubei Province, Hubei, PR China. 3 Taikang Center for Life and Medical Sciences of Wuhan University (1)
1Department of Hepatobiliary & Pancreatic Surgery, Zhongnan Hospital of Wuhan University, Wuhan, 430071, PR China. 2Clinical Medicine Research Center for Minimally Invasive Procedure of Hepatobiliary & Pancreatic Diseases of Hubei Province, Hubei, PR China. 3Taikang Center for Life and Medical Sciences of Wuhan University (1)
1Department of Pathology, Dana-Farber/Harvard Cancer Center, PhD Program in Immunology, Harvard Medical School; Department of Laboratory Medicine, Boston Children's Hospital, Enders Research Building, Room 811, Boston, MA, 02115, USA (1)
Biomedicine Discovery Institute and Department of Biochemistry & Molecular Biology, Monash University, Melbourne, VIC, Australia (1)
Department of Biochemistry Biophysics and Structural Biology, Department of Biochemistry and Molecular Biophysics, Washington University in St. Louis, St. Louis, Missouri, United States (1)
Department of Breast Surgery, The First Affiliated Hospital of Xi'an Jiaotong University, 277 West Yanta Road, 710061 Xi’an, People’s Republic of China. (1)
Department of Liver Surgery and Transplantation, Liver Cancer Institute, Zhongshan Hospital, Fudan University; Key Laboratory of Carcinogenesis and Cancer Invasion of Ministry of Education, Key Laboratory of Medical Epigenetics and Metabolism, Institutes of Biomedical Sciences, Fudan University, Shanghai 200032, China (1)
Department of Structural Biology, St. Jude Children’s Research Hospital, Memphis, TN 38105, USA Department of Molecular Machines and Signaling, Max Planck Institute of Biochemistry, Martinsried, Germany (1)
Doctor at Tongji Hospital, Huazhong University of Science and Technology, Wuhan, China (1)
Key Laboratory of Cell Proliferation and Differentiation of the Ministry of Education and State Key Laboratory of Membrane Biology, College of Life Sciences, Peking University (1)
MOE Key Laboratory of Biosystems Homeostasis & Protection, State Conservation Centre for Gene Resources of Endangered Wildlife, College of Life Sciences, Zhejiang University, Hangzhou 310058, P. R. China (1)
School of Animal Science and Technology, Genetic Breeding and Reproduction Laboratory, Southwest University, China;Chongqing Academy of Animal Husbandry Sciences, Pig Breeding Research Institute, China (1)

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Xiao-Chai-Hu Decoction Ameliorates Poly (I:C)-Induced Viral Pneumonia through Inhibiting Inflammatory Response and Modulating Serum Metabolism.

Not available

S-EPMC9296287 | biostudies-literature

Understanding the polypharmacological anticancer effects of Xiao Chai Hu Tang via a computational pharmacological model.

Not available

S-EPMC4043560 | biostudies-literature

Real-World Study on Chai-Shi-Jie-Du Granules for the Treatment of Dengue Fever and the Possible Mechanisms Based on Network Pharmacology.

Not available

S-EPMC10482559 | biostudies-literature

The trans-omics landscape of COVID-19

The outbreak of coronavirus disease 2019 (COVID-19) is a global health emergency. Various omics results have been reported for COVID-19, but the molecular hallmarks of COVID-19, especially in those patients without comorbidities, have not been fully investigated. Here we collect blood samples from 2...

2021-10-06 | MTBLS2542 | MetaboLights

Quantitative acetylome analysis reveals histone modifications that may predict prognosis in hepatitis B-related hepatocellular carcinoma

The post-translational modification of lysine acetylation is related to hepatocellular carcinoma (HCC), and understanding this relationship requires detailed knowledge about the acetylated proteome in HCC tissue and about differences in protein acetylation between cirrhosis and liver cancer. Here we...

ORGANISM(S): Homo sapiens (Human)

2021-09-08 | PXD014994 | Pride

Principles of isoform-specific targeted protein degradation engaging the C-degron E3 KLHDC2

Targeted protein degradation (TPD) via molecular glues or PROTACs (Proteolysis-targeting chimeras) is an up-and-coming drug modality holding promise to drug the “undrugabbles.” Further expanding the collection of targetable E3 ligases for TPD, we report the discovery of ligands targeting the C-END d...

ORGANISM(S): Homo sapiens (Human)

2025-01-18 | PXD051581 | Pride

Protac Tpd Ubiquitin Brd3 Klhdc2

LDLR c.415G > A causes familial hypercholesterolemia by weakening LDLR binding to LDL.

Not available

S-EPMC10956282 | biostudies-literature

Ultrasound-Assisted Removal of Tetracycline by a Fe/N-C Hybrids/H₂O₂ Fenton-like System.

Not available

S-EPMC6644124 | biostudies-literature

E3 ligase autoinhibition by C-degron mimicry maintains C-degron substrate fidelity.

Not available

S-EPMC10080726 | biostudies-literature